Fungal infections of the gastrointestinal tract in the immunocompromised host: an update.

Fungal infections of the gastrointestinal tract in the immunocompromised host: an update.
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DOI:
10.1097/pap.0000000000000016
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发表时间:
2014-07
影响因子:
6.7
通讯作者:
Milner DA Jr
Milner DA Jr
中科院分区:
医学3区
文献类型:
--
作者:
Lamps LW;Lai KK;Milner DA Jr

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真菌感染是免疫功能低下患者发病和死亡的最重要原因之一。随着免疫功能低下患者数量的增加,侵袭性真菌感染(包括胃肠道真菌感染)的发病率显著增加。免疫功能低下患者真菌感染的诊断可能特别成问题,因为这些患者可能存在非典型临床特征。虽然念珠菌属和曲霉属代表了大多数免疫功能低下患者人群中诊断的真菌,但其他真菌正在成为越来越常见的病原体,本文将重点介绍免疫功能低下患者中几种重要的新兴真菌感染。
Fungal infections are one of the most significant causes of morbidity and mortality in immunocompromised patients. The incidence of invasive fungal infections, including those of the gastrointestinal tract, has increased significantly as numbers of immunocompromised patients have increased. The diagnosis of fungal infections in immunocompromised patients may be particularly problematic as these patients may present with atypical clinical features. Although Candida and Aspergillus species represent the majority of fungi diagnosed in the immunocompromised patient population, other fungi are emerging as increasingly common pathogens, and this review will focus on several important emerging fungal infections in immunocompromised patients.