Differential specificities of single mitral cells in rabbit olfactory bulb for a homologous series of fatty acid odor molecules.
Differential specificities of single mitral cells in rabbit olfactory bulb for a homologous series of fatty acid odor molecules.
复制标题
兔嗅球中单个二尖瓣细胞对同源脂肪酸气味分子系列的差异特异性。
DOI：
10.1152/jn.1992.67.3.786
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发表时间：
1992
影响因子：
2.5
通讯作者：
Kazuyuki Imamura
中科院分区：
文献类型：
--
作者：
Kensaku Mori;N. Mataga;Kazuyuki Imamura
1.利用单单元尖峰放电和振荡局部场电位的细胞外记录，研究了单个二尖瓣细胞的分子特异性及其在兔嗅球中的位置。一组包含一系列同源脂肪酸的羧酸分子被用作气味刺激物。 2.对不同烃链长度的脂肪酸分子表现出兴奋反应的二尖瓣细胞位于嗅球背内侧的一个区域中彼此靠近。 3.背内侧区域的各个二尖瓣细胞倾向于对具有相似烃链长度或结构的脂肪酸气味分子子集做出反应。对不同链长的脂肪酸子集做出反应的二尖瓣细胞在该区域中分布有部分偏移的重叠。 4. 结果表明，气味分子的立体化学特征是由单个延髓神经元编码的。
1. The molecular specificities of single mitral cells and their locations in the rabbit olfactory bulb were studied using extracellular recordings of single-unit spike discharges and oscillatory local field potentials. A panel of carboxylic acid molecules including a homologous series of fatty acids was used as odor stimuli. 2. Mitral cells showing excitatory responses to fatty acid molecules of different hydrocarbon chain length were localized near each other in a region in the dorsomedial part of the olfactory bulb. 3. Individual mitral cells in the dorsomedial region tended to respond to subsets of fatty acid odor molecules having similar hydrocarbon chain length or structure. Mitral cells responding to subsets of fatty acids of different chain length were distributed with partially shifted overlaps in this region. 4. The results show that stereochemical features of odor molecules are encoded by individual bulbar neurons.