Altered heel-pad mechanical properties in patients with Type 2 diabetes mellitus
Altered heel-pad mechanical properties in patients with Type 2 diabetes mellitus
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DOI：
10.1046/j.1464-5491.2000.00394.x
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发表时间：
2000-12-01
影响因子：
3.5
通讯作者：
Chen, CY
中科院分区：
文献类型：
--
作者：
Hsu, TC;Wang, CL;Chen, CY
目的 比较有前足溃疡、无前足溃疡和年龄匹配的健康受试者的足跟垫机械性能。 方法 与其他组年龄匹配的 20 名健康受试者（第一组）的 40 个足跟、21 名无前足溃疡的糖尿病患者（第二组）的 42 个足跟和 12 名活动性前足溃疡的糖尿病患者的 14 个足跟的足跟垫力学性能采用自制的加卸载装置和10 MHz线阵超声换能器对Ⅲ组进行评估。结果三组的卸载后跟垫厚度、压缩指数和弹性模量没有差异。与第一组受试者（平均+/- SD，27.9 +/- 6.1%）相比，第二组（36.1 +/- 8.7%）和第三组患者（43.2 +/- 6.6%）的能量耗散率显着增加（P < 0.001）。 II 组和 III 组之间的这一比率也存在显着差异 (P = 0.003)。 结论 鞋跟垫中耗散的较高冲击能量可能会使 2 型糖尿病患者发生足部溃疡的风险更高。
Aims To compare the heel-pad mechanical properties in patients with Type 2 diabetes mellitus with forefoot ulceration, without forefoot ulceration and age-matched healthy subjects.Methods Heel-pad mechanical properties in 40 heels of 20 healthy subjects (group I) age-matched with the other groups, 42 heels of 21 diabetic patients without forefoot ulceration (group II), and 14 heels of 12 diabetic patients with active forefoot ulceration (group III) were assessed using a self-constructed loading-unloading device and a 10-MHz linear-array ultrasound transducer.Results There were no differences in the unloaded heel-pad thickness, compressibility index and elastic modulus between the three groups. When compared with group I subjects (mean +/- SD, 27.9 +/- 6.1%), a significant increase (P < 0.001) was found in both group II (36.1 +/- 8.7%) and group III patients (43.2 +/- 6.6%) for the energy dissipation ratio. This ratio was also significantly different (P = 0.003) between groups II and III.Conclusions The higher impact energy dissipated in the heel-pad may put patients with Type 2 diabetes at higher risk for developing foot ulceration.