Experience Shapes the Development of Neural Substrates of Face Processing in Human Ventral Temporal Cortex
Experience Shapes the Development of Neural Substrates of Face Processing in Human Ventral Temporal Cortex
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DOI：
10.1093/cercor/bhv314
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发表时间：
2017-02-01
期刊：
影响因子：
3.7
通讯作者：
Grill-Spector, Kalanit
中科院分区：
文献类型：
--
作者：
Golarai, Golijeh;Liberman, Alina;Grill-Spector, Kalanit
在成年人中，腹侧颞叶皮层（VTC）以可复制的拓扑结构代表面孔。然而，目前尚不清楚视觉体验在这种拓扑结构的发展中扮演什么角色。通过对儿童和成人的功能性磁共振成像，我们发现了一个连续的发展过程，即在7岁时，整个VTC的面部选择激活拓扑结构已经成熟，但面部选择的空间范围和程度在7岁后继续发展到成年。重要的是，无论是在VTC的分布多体素模式上，还是在面部选择区域的反应幅度上，自己和其他年龄的面孔都有不同的表现。这些结果提供了强有力的证据，证明从童年到成年的发育过程中，经历塑造了面部的皮层表征。我们的研究结果对经验和年龄在塑造人类VTC面部处理神经基质中的作用具有重要意义。
In adult humans, the ventral temporal cortex (VTC) represents faces in a reproducible topology. However, it is unknown what role visual experience plays in the development of this topology. Using functional magnetic resonance imaging in children and adults, we found a sequential development, in which the topology of face-selective activations across the VTC was matured by age 7, but the spatial extent and degree of face selectivity continued to develop past age 7 into adulthood. Importantly, own-and other-age faces were differentially represented, both in the distributed multivoxel patterns across the VTC, and also in the magnitude of responses of face-selective regions. These results provide strong evidence that experience shapes cortical representations of faces during development from childhood to adulthood. Our findings have important implications for the role of experience and age in shaping the neural substrates of face processing in the human VTC.