Periodontitis, tooth loss and cognitive functions among older adults
Periodontitis, tooth loss and cognitive functions among older adults
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DOI：
10.1007/s00784-017-2307-8
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发表时间：
2018-06-01
影响因子：
3.4
通讯作者：
Renvert, Stefan
中科院分区：
文献类型：
--
作者：
Nilsson, Helena;Berglund, Johan Sanmartin;Renvert, Stefan
目的本研究的目的是评估牙周炎，牙齿的数量和认知功能在一个队列中的老年人在Sweden.Materials和方法之间的潜在关联在总的，775个人从60至99岁的年龄被选中的研究。进行了临床和影像学检查。计算牙齿数量、牙周袋和骨质流失的患病率并进行分类。认知功能评估采用简易精神状态检查（MMSE）和时钟测试。教育水平通过问卷调查获得。结果年龄和性别与骨丢失的患病率相关。年龄和教育程度与牙齿数量较少有关。性别也与口袋的存在有关。多因素Logistic回归分析显示，MMSE测试结果与骨丢失率、牙齿数量有显著相关性。即使在调整了年龄、教育和性别之后，这种关联仍然存在。牙齿缺失也与时钟测试结果较低相关。牙周袋的存在>= 5 mm与认知测试outcome.Conclusions牙周炎和牙齿脱落的历史可能是老年人的认知功能的重要性。
Objectives This study aims to evaluate the potential association between periodontitis, the number of teeth and cognitive functions in a cohort of older adults in Sweden.Materials and methods In total, 775 individuals from 60 to 99 years of age were selected for the study. A clinical and radiographic examination was performed. The number of teeth and prevalence of periodontal pockets and bone loss was calculated and categorised. Cognitive functions were assessed using the Mini-Mental State Examination (MMSE) and clock test. The education level was obtained from a questionnaire. Data were analysed using chi-square tests and multivariate logistic regression.Results Age and gender were associated with the prevalence of bone loss. Age and education were associated with lower number of teeth. Gender was also associated with the presence of pockets. The multivariate logistic regression analysis demonstrated a statistically significant association between prevalence of bone loss, the number of teeth and the outcome on MMSE test. This association remained even after adjustment for age, education and gender. Tooth loss was also associated with lower outcome on clock test. Presence of periodontal pockets >= 5 mm was not associated with cognitive test outcome.Conclusions A history of periodontitis and tooth loss may be of importance for cognitive functions among older adults.