Emission and absorption properties of indocyanine green in Intralipid solution
Emission and absorption properties of indocyanine green in Intralipid solution
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DOI：
10.1117/1.1695411
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发表时间：
2004-05-01
影响因子：
3.5
通讯作者：
Zhu, Q
中科院分区：
文献类型：
--
作者：
Yuan, BH;Chen, NG;Zhu, Q
研究了吲哚菁绿色（ICG）在Intraperoid溶液中的发射和吸收特性。该研究集中在0至20 AM范围内相对较低的ICG浓度。采用扩散模型分析了不同浓度ICG溶液的发射特性。在低浓度区，发射强度随ICG浓度的增加而增加，而在高浓度区，发射强度随ICG浓度的增加而减小。一般来说，存在最大发射强度，其位置（浓度）取决于激发光的波长、光源和检测器之间的距离以及样品的几何形状和尺寸。一个所谓的“内细胞效应”和发射光子的重吸收被发现有助于发射强度的衰减。在0 ~ 2 μ M的浓度范围内，ICG溶液在830 nm处的吸收系数总是高于660 nm处的吸收系数，这与ICG在水溶液中的吸收系数有很大的不同。(C)2004年，美国光电仪器工程师学会。
Emission and absorption properties of indocyanine green (ICG) in Intralipid solution have been investigated. The study is focused on relatively low ICG concentration at a range of 0 to 20 AM. A diffusion model was used to analyze the emission properties of ICG solution at different concentrations. In the low-concentration region, the emission strength increases with the concentration of ICG, while in the high-concentration region, the emission decreases with the concentration. In general, a maximum of emission strength exists and its position (concentration) depends on the wavelength of the excitation light, the distance between the source and the detector, and the sample geometry and size. A so-called "inner-cell-effect" and reabsorption of emission photons are found to contribute to the decay of emission strength. Also, in the concentration range of 0 to 2 muM, ICG solution always has a higher absorption coefficient at wavelength 830 nm than that at 660 nm, which is quite different from the ICG in water case. (C) 2004 Society of Photo-Optical Instrumentation Engineers.