SYNTHESIS OF OPTICALLY ACTIVE TELEOCIDIN DERIVATIVES. ABSOLUTE CONFIGURATION OF TELEOCIDIN B AND OLIVORETIN A
SYNTHESIS OF OPTICALLY ACTIVE TELEOCIDIN DERIVATIVES. ABSOLUTE CONFIGURATION OF TELEOCIDIN B AND OLIVORETIN A
复制标题
光学活性 Teleocidin 衍生物的合成。
DOI：
10.1248/cpb.32.358
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发表时间：
1984
影响因子：
1.7
通讯作者：
Y. Koyama
中科院分区：
文献类型：
--
作者：
Y. Endo;K. Shudo;K. Furuhata;H. Ogura;S. Sakai;N. Aimi;Y. Hitotsuyanagi;Y. Koyama
以 N-Boc-4-硝基-L-色氨酸为原料合成了光学活性 3, 4, 5, 6, 7, 8-六氢-4 (S)-羟甲基-7 (S)-异丙基-8-甲基-6-氧代 [1, 4] 重氮基 [7, 6, 5-cd] 吲哚，对该化合物的圆二色性研究表明，teleocidin B 的九元环和olivoretin A 为 S, S 构型。
Optically active 3, 4, 5, 6, 7, 8-hexahydro-4 (S)-hydroxymethyl-7 (S)-isopropyl-8-methyl-6-oxo [1, 4] diazonino [7, 6, 5-cd] indole was synthesized from N-Boc-4-nitro-L-tryptophanol and a circular dichroism study of the compound shows that the nine-membered ring of teleocidin B and olivoretin A is S, S configuration.