Deformation response of paired donor corneas to an air puff: Intact whole globe versus mounted corneoscleral rim
Deformation response of paired donor corneas to an air puff: Intact whole globe versus mounted corneoscleral rim
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DOI：
10.1016/j.jcrs.2014.02.032
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发表时间：
2014-06-01
影响因子：
2.8
通讯作者：
Roberts, Cynthia J.
中科院分区：
文献类型：
--
作者：
Metzler, Kimberly M.;Mahmoud, Ashraf M.;Roberts, Cynthia J.
目得：评价眼壳生物力学特性对角膜变形反应的影响，以空气puff.SETTING：俄亥俄州州立大学，哥伦布，俄亥俄州，美国。设计：实验研究。方法：24眼的12个人类捐赠者获得配对。将一只眼睛固定在专门设计的全地球仪支架上（全地球仪组）。将对侧眼角膜置于巴伦人工前房中（人工前房组）。将角膜依次安装并连接到压力控制系统。使用Corvis ST（一种动态Scheimpflug分析仪）采集变形数据。内部压力被设置为10，20，30，40，和50毫米汞柱;至少4次检查，在每个pressure.RESULTS：统计学显着较高的最大变形幅度观察到在全球组比在人工室组在所有的压力。在10、20、30、40和50 mm Hg时，平均振幅差分别为1.006 mm +/- 0.238 [SD]、0.614 +/- 0.137 mm、0.384 +/- 0.099 mm、0.229 +/- 0.087 mm和0.133 +/- 0.068 mm（P
PURPOSE: To evaluate the influence of ocular shell biomechanical characteristics on corneal deformation response to an air puff.SETTING: The Ohio State University, Columbus, Ohio, USA.DESIGN: Experimental study.METHODS: Twenty-four eyes of 12 human donors were obtained in matched pairs. One eye was secured in a purpose-designed whole globe mount (whole-globe group). The cornea from the fellow eye was placed in a Barron artificial anterior chamber (artificial-chamber group). The corneas were mounted sequentially and connected to a pressure-control system. Deformation data were acquired using the Corvis ST, a dynamic Scheimpflug analyzer. Internal pressure was set to 10, 20, 30, 40, and 50 mm Hg; at least 4 examinations were performed at each pressure.RESULTS: Statistically significantly higher maximum deformation amplitude was observed in the whole-globe group than in the artificial-chamber group at all pressures. The mean amplitude differences were 1.006 mm +/- 0.238 [SD], 0.614 +/- 0.137 mm, 0.384 +/- 0.099 mm, 0.229 +/- 0.087 mm, and 0.133 +/- 0.068 mm at 10, 20, 30, 40, and 50 mm Hg, respectively (P