POWER AND SAMPLE-SIZE CALCULATIONS - A REVIEW AND COMPUTER-PROGRAM
POWER AND SAMPLE-SIZE CALCULATIONS - A REVIEW AND COMPUTER-PROGRAM
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DOI：
10.1016/0197-2456(90)90005-m
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发表时间：
1990-04-01
期刊：
影响因子：
--
通讯作者：
PLUMMER, WD
中科院分区：
文献类型：
--
作者：
DUPONT, WD;PLUMMER, WD
最常见的研究设计的样本量和功率计算方法进行了审查。这些设计的样本量和功效方程是样本量和功效计算的两个通用公式的特例。有一个计算机程序可用于二分、连续或生存反应指标的研究。可根据不同的缓解率、平均值或生存时间，或根据相对风险或比值比来指定感兴趣的备择假设。具有二分或连续结局的研究可能涉及匹配或独立的研究设计。该程序可以确定检测具有所需功效的指定备择假设所需的样本量，可以使用给定样本量检测特定备择假设的功效，或者可以使用给定功效和样本量检测的特定备择假设。该程序可以根据请求生成帮助信息，以方便使用该软件。它写入所有计算估计的日志文件，并可以生成用于绘制功率曲线的输出文件。它是用FORTRAN-77编写的，属于公共领域。
Methods of sample size and power calculations are reviewed for the most common study designs. The sample size and power equations for these designs are shown to be special cases of two generic formulae for sample size and power calculations. A computer program is available that can be used for studies with dichotomous, continuous, or survival response measures. The alternative hypothesis of interest may be specified either in terms of differing response rates, means, or survival times, or in terms of relative risks or odds ratios. Studies with dichotomous or continuous outcomes may involve either a matched or independent study design. The program can determine the sample size needed to detect a specified alternative hypothesis with the required power, the power with which a specific alternative hypothesis can be detected with a given sample size, or the specific alternative hypotheses that can be detected with a given power and samples size. The program can generate help messages on request that facilitate the use of this software. It writes a log file of all calculated estimates and can produce an output file for plotting power curves. It is written in FORTRAN-77 and is in the public domain.