Corneal anesthetics and epithelial oxygen flux.
Corneal anesthetics and epithelial oxygen flux.
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角膜麻醉剂和上皮氧通量。
DOI：
10.1001/archopht.1972.01000030307016
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发表时间：
1972
影响因子：
--
通讯作者：
R. Hill
中科院分区：
文献类型：
--
作者：
A. Augsburger;R. Hill
在体内比较了三种表面麻醉剂可卡因、丁卡因(蓬托卡因)和盐酸苯磺酸钠对泪液上皮界面氧通量的影响。虽然在苯磺酸的情况下，角膜止痛并不伴随着流量抑制，但可卡因和丁卡因都会发生这种情况。在这两种情况下，止痛在开始时总是导致流量下降，但在恢复过程中这两种现象的相互关系并不是很清楚。
The effects of three topical anesthetics, cocaine, tetracaine (Pontocaine), and benoxinate hydrochloride, on oxygen flux across the tear-epithelial interface were compared in vivo at three dosage levels. Although flux depression did not accompany corneal analgesia in the case of benoxinate, it did occur with both cocaine and tetracaine. In both these cases, analgesia always led flux depression at onset, yet the interrelationship of the two phenomena was not so clearly defined during recovery.