The treatment and prognosis of Hurthle cell follicular thyroid carcinoma compared with its non-Hurthle cell counterpart
The treatment and prognosis of Hurthle cell follicular thyroid carcinoma compared with its non-Hurthle cell counterpart
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DOI：
10.1016/j.surg.2005.08.034
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发表时间：
2005-12-01
期刊：
影响因子：
3.8
通讯作者：
Urbach, DR
中科院分区：
文献类型：
--
作者：
Haigh, PI;Urbach, DR
背景本研究比较了Hurthle细胞甲状腺滤泡癌（HCFC）和非HCFC的治疗和预后。监测、流行病学和最终结果数据库确定了1988年至1993年期间使用氟氯烃和不使用氟氯烃的患者，并对这些患者进行了跟踪，直至2001年。比较两组患者的治疗方法，分析影响预后的因素。确定了845名患者; 172名患者（20%）使用氯氟烃，673名患者（80%）使用非氯氟烃。全甲状腺切除术在80%的HCFC患者中进行，而非HCFC患者为69%（P =. 005）。使用放射性碘的HCFC患者占33%，非HCFC患者占45%（P 0.003）。氟氯烃患者的粗10年生存率为73%，非氟氯烃患者的粗10年生存率为83%。年龄较大（>= 50 vs 5 vs 10 cm vs
Background. This population study compared the treatment and Prognosis of Hurthle cell follicular thyroid carcinoma (HCFC) and non-HCFC.Methods. The Surveillance, Epidemiology and End Results database identified patients with HCFC and non-HCFC from 1988 to 1993 who were followed to 2001. Treatment Of each carcinoma was compared, and the effect of prognostic factors on survival was analyzed.Results. Eight hundred forty-five patients were identified; 172 patients (20%) had HCFC and 6 73 patients (80%) had non-HCFC. Total thyroidectomy was performed in 80% of patients with HCFC compared with 69% with non-HCFC (P =. 005). Radioactive iodine was used in 33% with HCFC and 45% with non-HCFC (P 003). The crude 10-year survival was 73% in HCFC and 83% in non-HCFC patients. Older age (>= 50 vs 5 vs 10 cm vs