The myth of the 50-50 breast
The myth of the 50-50 breast
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DOI：
10.1118/1.3250863
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发表时间：
2009-12-01
期刊：
影响因子：
3.8
通讯作者：
Brock, K.
中科院分区：
文献类型：
--
作者：
Yaffe, M. J.;Boone, J. M.;Brock, K.
目的：对于剂量测定和乳房X射线成像的优化工作，通常假设乳房由50%的纤维腺体组织和50%的脂肪组成。本研究的目的是评估这种假设是否是现实的。方法：首先，从实验乳腺CT扫描仪获得的数据被用来验证一种算法，从数字化的电影乳房X线照片测量乳腺密度。密度结果获得的2831名妇女，包括191名妇女接受CT和乳房X线照片的2640名妇女从其他三个groups.Results：平均组成，表示为纤维腺体组织（包括皮肤）的百分比，从13.7%到25.6%的群体之间的总体平均值为19.3%，然后被用来估计乳房compositions.Results：平均组成。乳房X线照片的平均压缩乳房厚度为5.9 cm（σ = 1.6 cm）。80%的女性乳房体积密度小于27%，95%的女性乳房体积密度小于45%。结论：根据本研究中四组女性的结果，“50-50”乳房不是乳房组成的代表性模型。(C)2009年美国医学物理学家协会。[DOI：10.1118/1.3250863]
Purpose: For dosimetry and for work in optimization of x-ray imaging of the breast, it is commonly assumed that the breast is composed of 50% fibroglandular tissue and 50% fat. The purpose of this study was to assess whether this assumption was realistic.Methods: First, data obtained from an experimental breast CT scanner were used to validate an algorithm that measures breast density from digitized film mammograms. Density results obtained from a total of 2831 women, including 191 women receiving CT and from mammograms of 2640 women from three other groups, were then used to estimate breast compositions.Results: Mean compositions, expressed as percent fibroglandular tissue (including the skin), varied from 13.7% to 25.6% among the groups with an overall mean of 19.3%. The mean compressed breast thickness for the mammograms was 5.9 cm (sigma = 1.6 cm). 80% of the women in our study had volumetric breast density less than 27% and 95% were below 45%.Conclusions: Based on the results obtained from the four groups of women in our study, the "50-50" breast is not a representative model of the breast composition. (C) 2009 American Association of Physicists in Medicine. [DOI: 10.1118/1.3250863]