Interactions between sleep, other body rhythms, immune responses, and exercise.
Interactions between sleep, other body rhythms, immune responses, and exercise.
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睡眠、其他身体节律、免疫反应和运动之间的相互作用。
DOI：
10.1139/h97-009
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
P. Shek
中科院分区：
文献类型：
--
作者：
R. Shephard;P. Shek
生物节律会影响运动耐量和免疫功能。大多数研究都集中在昼夜节律上，但也描述了一些昼夜节律、昼夜节律和昼夜节律。节奏可以有内源性基础，也可以有外源性基础。内源性节律起源于视交叉上核的细胞。来自这一区域的冲动传递到松果体，在那里它们调节褪黑素的产生，褪黑素是一种调节睡眠/清醒周期的化合物。内分泌、生理和心理参数都显示出周期性的证据。免疫系统的大多数组成部分，包括细胞和体液，也显示出很大的节律性变化。目前尚不清楚这种周期性与其他身体系统的变化相比在多大程度上是次要的。然而，变化的幅度如此之大，以至于在运动和免疫功能的急性和慢性研究中，在相同的时间点获得实验和对照数据是至关重要的。睡眠/觉醒周期的紊乱可能构成一种压力，对免疫功能造成不良后果。
Biological rhythms can influence both exercise tolerance and immune function. Most studies have focussed upon circadian rhythms, but some circaseptan, circatrigintan, and circannual cycles have also been described. Rhythms may have an endogenous or an exogenous basis. Endogenous rhythms originate in the cells of the suprachiasmatic nucleus. Impulses from this region pass to the pineal gland, where they regulate the production of melatonin, a compound that modulates the sleep/wakefulness cycle. Endocrine, physiological, and psychological parameters all show evidence of periodicity. Most components of the immune system, both cellular and humoral, also show large rhythmic changes. It is not yet clear how far such periodicity is secondary to changes in other body systems. Nevertheless, the magnitude of variation is such that it is vital to obtain experimental and control data at identical time points in both acute and chronic studies of exercise and immune function. Disturbance of the sleep/wakefulness cycle can constitute a form of stress, with adverse consequence for immune function.