Self-Medication with Antibiotics Among Children in China: A Cross-Sectional Study of Parents' Knowledge, Attitudes, and Practices.
Self-Medication with Antibiotics Among Children in China: A Cross-Sectional Study of Parents' Knowledge, Attitudes, and Practices.
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DOI：
10.2147/idr.s431034
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发表时间：
2023
影响因子：
3.9
通讯作者：
中科院分区：
文献类型：
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在低收入和中等收入国家，儿童自行服用抗生素是一种常见做法，这加速了抗菌药物的滥用。本研究旨在评估中国儿童SMA的患病率及其相关因素，包括父母对抗生素使用的知识、态度和实践。本研究于2020年7月至9月在南通市开展了一项基于结构化问卷调查的横断面研究。共有1699名受访者参与了调查。收集了参与者的人口统计和家庭特征、对抗生素使用的知识、态度和做法等信息。采用层次二元逻辑回归检验儿童SMA的预测因素。在1699名参与者中，23.31%的人在过去一年中对他们的孩子进行了SMA。咳嗽（59.6%）是导致自我药疗的最常见症状，青霉素（85.4%）是最常用药物。分层回归结果显示，无论是在城市还是农村，抗生素知识得分较高（OR=1.163, 95% CI: 1.067 ~ 1.268）和无处方从药店购买抗生素（OR=1.475, 95% CI: 1.097 ~ 1.983）的父母更有可能对孩子实施SMA。在家中储存抗生素导致城市地区自我药疗的可能性增加，但在农村地区则不然。此外，无慢性疾病的儿童使用非处方抗生素的概率也较高（OR=1.959, 95% CI:1.072 ~ 3.578）。在中国，儿童SMA的患病率很高。较高的知识得分和购买和储存非处方抗生素行为的做法增加了父母对儿童抗生素自我用药的使用。切实有效的儿童抗生素合理使用教育干预亟须加强。
Self-medication with antibiotics (SMA) among children is a common practice in low-income and middle-income countries, which has accelerated antibacterial abuse. This study aimed to estimate the prevalence and associated factors of SMA among children in China, including parents’ knowledge, attitudes, and practices towards antibiotic use. A cross-sectional study based on a structured questionnaire survey of parents was conducted in Nantong between July and September 2020. A total of 1699 respondents participated. Information on participants’ demographic and family characteristics, knowledge, attitudes, and practices towards antibiotics use was collected. Hierarchical binary logistic regression was used to examine the predictors of SMA among children. Among 1699 participants, 23.31% practiced SMA to their children in the past year. Cough (59.6%) was the most common symptom leading to self-medication and penicillins (85.4%) were the most commonly used drugs. Hierarchical regression indicated that parents with higher level of antibiotic knowledge scores (OR=1.163, 95% CI: 1.067–1.268) and buying antibiotics without a prescription from pharmacy (OR=1.475, 95% CI: 1.097–1.983) were more likely to practice SMA to their children both in urban and in rural areas. Storing antibiotics at home resulted in an increased likelihood of self-medication in urban areas but not in rural areas. In addition, there was also a higher probability of non-prescribed antibiotics in children without chronic diseases (OR=1.959, 95% CI:1.072–3.578). The prevalence of SMA in children is high in China. Higher knowledge scores and practices of buying and storing non-prescribed antibiotics behaviors increased parents’ antibiotic self-medication in their children. Practical and effective education intervention for children’s rational use of antibiotics is urgently strengthened.