Highly enantioselective hydrogenation of alpha-aryl-beta-substituted acrylic acids catalyzed by Ir-SpinPHOX.

Highly enantioselective hydrogenation of alpha-aryl-beta-substituted acrylic acids catalyzed by Ir-SpinPHOX.
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DOI:
10.1039/b919902k
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发表时间:
2010-01
影响因子:
4.9
通讯作者:
Yi Zhang;Zhaobin Han;Fu-ying Li;K. Ding;A. Zhang
Yi Zhang;Zhaobin Han;Fu-ying Li;K. Ding;A. Zhang
中科院分区:
化学2区
文献类型:
--
作者:
Yi Zhang;Zhaobin Han;Fu-ying Li;K. Ding;A. Zhang

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The enantioselective hydrogenation of a series of challenging substrates, alpha-aryl-beta-substituted acrylic acids, was realized with high efficiency and enantioselectivity (up to 96%) under the catalysis of Ir(i) complex of Spiro-based P,N ligand, SpinPHOX.