Comparison between noninvasive indices of baroreceptor sensitivity and the phenylephrine method in post-myocardial infarction patients
Comparison between noninvasive indices of baroreceptor sensitivity and the phenylephrine method in post-myocardial infarction patients
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DOI：
10.1161/01.cir.97.14.1362
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发表时间：
1998-04-14
期刊：
影响因子：
37.8
通讯作者：
Rizzon, P
中科院分区：
文献类型：
--
作者：
Pitzalis, MV;Mastropasqua, F;Rizzon, P
背景-苯肾上腺素试验获得的压力感受器反射敏感性降低对有心肌梗死病史的患者具有预后作用。我们的目的是评估苯肾上腺素和两种非侵入性方法获得的压力反射敏感性之间的相关性和一致性：α指数和序列分析.方法和结果α指数是通过对RR和收缩压在高、低频带的变异性进行频谱分析来测量的;从同时记录的RR和收缩压同时升高或降低的时间序列中识别序列，在自主呼吸和控制呼吸期间进行无创压力反射敏感性测试，对52例近期心肌梗死的连续患者进行了分析，尽管苯肾上腺素与任何一种非侵入性方法之间的相关性总是显著的，但在控制呼吸时发现的相关性最高（r=.70），然而，通过以下方法计算的一致性限度，Bland和Altman方法的平均值对于两种非侵入性方法都很宽。结论-通过无创压力反射敏感性评估获得的结果不应在临床实践中用作苯肾上腺素方法获得的结果的替代。
Background-Depressed baroreflex sensitivity obtained by means of a phenylephrine test plays a prognostic role in patients with a previous myocardial infarction. Our purpose was to evaluate the correlation and agreement between the baroreflex sensitivity obtained with phenylephrine and that obtained by two noninvasive methods: the alpha-index and sequence analysis.Methods and Results-The alpha-index was measured by means of the spectral analysis of RR and systolic blood pressure variabilities in both the high-and low-frequency bands; sequences were identified from simultaneously recorded time series in which the RR and systolic blood pressure concurrently increased or decreased, Noninvasive baroreflex sensitivity tests were performed during both spontaneous and controlled respiration, Fifty-two consecutive patients with recent myocardial infarction underwent the analyses, Although the correlations between phenylephrine and either of the noninvasive methods were always significant, those found during controlled respiration had the highest r values (r=.70), However, the Limits of agreement calculated by,means of the Bland and Altman method were wide for both noninvasive methods.Conclusions-The results obtained by means of noninvasive baroreflex sensitivity assessments should not be used in clinical practice as an alternative to those obtained by the phenylephrine method.