Defensive hostility: relationship to multiple markers of cardiac ischemia in patients with coronary disease.
Defensive hostility: relationship to multiple markers of cardiac ischemia in patients with coronary disease.
复制标题
防御性敌意：与冠心病患者心肌缺血多种标志物的关系。
DOI：
10.1037//0278-6133.14.3.202
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Rozanski,A
中科院分区：
文献类型：
--
作者：
Helmers,KF;Krantz,DS;Merz,CN;Klein,J;Kop,WJ;Gottdiener,JS;Rozanski,A
三项研究评估了敌意和防御性的综合特征是否能识别出一组患有功能性严重冠状动脉疾病（CAD）的敌意个体。CAD患者完成Cook-Medley敌意量表（Ho）和Marlowe-Crowne社会期望量表（MC）。将患者分为4组：防御性敌对（DH：高Ho，高MC）、低敌对（LH：低Ho，低MC）、高敌对（HH：高Ho，低MC）和防御性（Def：低Ho，高MC）。与HH、LH和Def CAD患者相比，DH患者表现出最大的灌注缺陷（通过运动铊造影测量）; DH患者在动态心电图监测期间表现出最频繁的缺血发作;在实验室研究中，DH患者表现出最严重的精神应激诱导的缺血（通过超声心动图评估）。因此，高敌意和高防御性的组合与更严重的CAD功能相关，并可能使CAD患者预后更差。
Three studies assessed whether the combined traits of hostility and defensiveness identify a group of hostile individuals with functionally severe coronary artery disease (CAD). CAD patients completed the Cook–Medley Hostility Inventory (Ho) and the Marlowe-Crowne Social Desirability Scale (MC). Patients were classified into 4 groups: defensive hostile (DH: high Ho, high MC), low hostile (LH: low Ho, low MC), high hostile (HH: high Ho, low MC), and defensive (Def: low Ho, high MC). DH in comparison to HH, LH, and Def CAD patients demonstrate the greatest perfusion defects as measured by exercise thallium scintigraphy; DH patients exhibit the most frequent ischemic episodes during ambulatory electrocardiographic monitoring; and in a laboratory study, DH patients exhibit the most severe mental stress-induced ischemia assessed by echocardiography. Thus, the combination of high hostility and high defensiveness are associated with more functionally severe CAD and may predispose CAD patients to a more adverse prognosis.