Predictive factors for the use of complementary and alternative medicine (CAM) in radiation oncology
Predictive factors for the use of complementary and alternative medicine (CAM) in radiation oncology
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DOI：
10.1016/j.eujim.2009.02.001
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发表时间：
2009-04-01
影响因子：
2.5
通讯作者：
Buentzel, Jens
中科院分区：
文献类型：
--
作者：
Micke, Oliver;Bruns, Frank;Buentzel, Jens
简介：进行了一项多中心研究，以确定预测放射治疗患者使用补充和替代医学（CAM）的因素，为患者提供他们所要求的信息和支持。方法：使用结构化问卷采访了总共1013名连续接受放射治疗的恶性疾病患者。多因素Logistic逐步回归分析replies.Results：共有59%的患者报告使用CAM疗法。CAM的使用在女性患者中更常见，通常在晚期更高，最常见于乳腺癌，其次是霍奇金病，其他妇科恶性肿瘤，肾细胞癌，直肠癌和前列腺癌。最常报道的CAM疗法是维生素、槲寄生、硒和其他微量元素。多因素Logistic逐步回归分析显示，年龄、性别、肿瘤类型和分期、吸烟行为是CAM使用的显著预测因素。最高的相对危险度（RR）计算为乳腺癌患者，而最低的RR计算为头部和颈部cancerpatients.Discussion：这项研究是最大的分析CAM放疗癌症患者之间的使用。接受放射治疗的癌症患者中有一半以上使用CAM。一般来说，典型的CAM使用者是患有乳腺癌的女性患者，不吸烟，不饮酒，患有晚期疾病，并接受治疗。(C)2009年Elsevier GmbH。All rights reserved.
Introduction: A multi-center study was performed to identify factors predicting the use of complementary and alternative medicine (CAM) in radiotherapy patients, giving patients the information and the support they request.Methodology: A total of 1013 consecutive patients receiving radiotherapy for malignant diseases were interviewed using a structured questionnaire. Multivariate logistic stepwise backward regression was used to analyze the replies.Results: A total of 59% of patients reported using CAM therapies. CAM use was more common in female patients, generally higher in advanced stages, and most common in breast cancer, followed by Hodgkin's disease, other gynecologic malignancies, renal cell carcinoma, rectal cancer, and prostate cancer. The most frequently reported CAM therapies were vitamins, mistletoe, selenium, and other trace elements. Multivariate logistic stepwise backward regression showed that age, gender, tumor type and stage, and smoking behavior were significant predictors of CAM use. The highest relative risk (RR) was calculated for breast cancer patients, while the lowest RR was calculated for head and neck cancer patients.Discussion: This study represents the largest analysis of CAM use among radiotherapy cancer patients. More than half of the patients undergoing radiotherapy for cancer were using CAM. In general, the typical CAM user was a female patient suffering from breast cancer, a non-smoker and non-drinker, had an advanced stage of disease, and was treated with curative intentions. (C) 2009 Elsevier GmbH. All rights reserved.