A Comprehensive Review of Radiosurgery for Cerebral Arteriovenous Malformations: Outcomes, Predictive Factors, and Grading Scales
A Comprehensive Review of Radiosurgery for Cerebral Arteriovenous Malformations: Outcomes, Predictive Factors, and Grading Scales
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脑动静脉畸形放射外科的综合评价：结果、预测因素和分级量表
DOI：
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发表时间：
2008
影响因子：
1.7
通讯作者：
E. Connolly Jr.
中科院分区：
文献类型：
--
作者：
R. Starke;R. Komotar;Brian Y. Hwang;Laura E Fischer;M. Otten;M. Merkow;M. Garrett;S. Isaacson;E. Connolly Jr.
脑动静脉畸形（AVMs）的治疗仍然是神经外科医生面临的一个挑战。这种疾病的自然历史，以及治疗干预的发病率和死亡率，仍然不完全阐明。AVM管理中的预测因素和分级量表允许对治疗方案进行风险-收益分析和结果比较。立体定向放射手术是avm的既定治疗方式之一，通常用于治疗手术切除的高风险病变。放射外科手术的目的是消除动静脉畸形，从而防止出血或癫痫发作，而不会出现任何新的或恶化的现有症状。病变特征和术后并发症在放射手术与显微手术治疗的患者中有显著差异。基于放射外科的分级系统考虑了与放射外科结果的各个方面相关的因素，包括闭塞、出血和术后并发症，特别是由放射引起的并发症。本文的目的是描述最新的预测因素和分级系统的放射外科治疗脑动静脉畸形。
The management of cerebral arteriovenous malformations (AVMs) continues to present a challenge to neurosurgeons. The natural history of this condition, as well as the morbidity and mortality of therapeutic interventions, remains incompletely elucidated. Predictive factors and grading scales in AVM management allow risk-benefit analysis of treatment options and comparison of outcomes. Stereotactic radiosurgery is one of the established treatment modalities for AVMs and is generally used to treat lesions that are high risk for surgical resection. Radiosurgery aims to obliterate AVMs and thus prevent hemorrhage or seizure without any new or worsening of existing symptoms. Lesion characteristics and postsurgical complications differ markedly in patientstreated by radiosurgery versus microsurgery. Radiosurgery-based grading systems account for factors that have been associated with various aspects of radiosurgical outcomes including obliteration, hemorrhage, and postoperative complications, particularly those induced by radiation. The purpose of this paper is to describe the most current predictive factors and grading systems for radiosurgical treatment of cerebral AVMs.
影响因子：
8.3
作者：
Hartmann, A;Mast, H;Young, WL
通讯作者：
Young, WL