Revisiting the children of twins: Can they be used to resolve the environmental effects of dyadic parental treatment on child behavior?

Revisiting the children of twins: Can they be used to resolve the environmental effects of dyadic parental treatment on child behavior?
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DOI:
10.1375/twin.8.4.283
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发表时间:
2005-08-01
影响因子:
0.9
通讯作者:
Maes, HH
Maes, HH
中科院分区:
医学4区
文献类型:
--
作者:
Eaves, LJ;Silberg, JL;Maes, HH

文献摘要

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双胞胎的子女(COT)设计已被提出作为一种替代的收养研究,以解决直接影响的父母治疗的次级亲子关系,由于遗传因素。基本的分析方法比较了父母与子女之间的相关性和他们父母的同卵(MZ)双胞胎之间的相关性。我们发现,这些相关性之间的显着差异并不意味着直接的环境因果关系时,所测量的父母治疗的问题是二元的,也就是说,受父母双方,即使交配是随机的。非遗传的因果效应产生非常相似的模式的相关性二进治疗变量的二级遗传效应。事实上,许多候选环境,如父母离婚,是二元的,这使得人们有理由质疑他们与双胞胎子女行为相关性的解释。
T he children of twins (COT) design has been proposed as an alternative to the adoption study to resolve the direct effects of parental treatment from secondary parent-child association due to genetic factors. The basic analytical approach compares the parent-offspring correlation with the correlation between children and the monozygotic (MZ) twins of their parents. We show that a significant difference between these correlations does not imply direct environmental causality when the measured parental treatment in question is dyadic, that is, influenced by both parents even when mating is random. Nongenetic causal effects yield very similar patterns of correlation to secondary genetic effects on dyadic treatment variables. The fact that many candidate environments, such as parental divorce, are dyadic gives reason to question the interpretation of their correlations with behavior in the children of twins.