Increasing tuberculosis incidence and its relationship to acquired immunodeficiency syndrome in New York City [abstract]

Increasing tuberculosis incidence and its relationship to acquired immunodeficiency syndrome in New York City [abstract]
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纽约市结核病发病率上升及其与获得性免疫缺陷综合征的关系[摘要]

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发表时间:
1985
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影响因子:
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通讯作者:
A. Kristal
A. Kristal
中科院分区:
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作者:
Stoneburner Rl;A. Kristal

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最近纽约市(NYC)结核病发病率的增加可能与获得性免疫缺陷综合征(AIDS)的流行有关。作者检查了纽约结核病登记处、1981-84年与毒品有关的死亡病例的艾滋病监测数据和1980年美国人口普查数据,以寻找这种联系的证据。在报告的2452名艾滋病患者中,有133人也患有结核病。其中91%是男性;97%是15-54岁之间的人;49%是静脉吸毒者;9%是海地移民。与1980年至1983年艾滋病发病率上升相一致,15-54岁男性结核病发病率从31/100000上升到41/100000,增幅为33%(p.001)。其他组均未见明显增加。这一增长中的33%可归因于报告的艾滋病患者中的结核病。男性结核病发病率最大的增长出现在艾滋病危险群体人口较多的5个卫生区:4个卫生区静脉注射吸毒者,增加55%;海地移民在1个卫生区,增加59%。结核病发病率上升的卫生区与艾滋病风险因素之间存在生态关联。对这些人群中的结核病病例进行HTLV-III/LAV感染的血清学调查将有助于确定这种关系是否具有因果关系。(全文)
Recent increases in tuberculosis (TB) incidence in New York City (NYC) may be related to the epidemic of acquired immunodeficiency syndrome (AIDS). The authors examined the NYC TB registry AIDS surveillance data from 1981-84 narcotic-related deaths and 1980 US census data to find evidence of this association. Of 2452 persons reported with AIDS 133 also had TB. 91% of these were male; 97% were between 15-54 years of age; 49% were intravenous drug users; and 9% were Haitian immigrants. Coincident to increasing incidence of AIDS from 1980 through 1983 incidence rates of TB in males age 15-54 increased 33% from 31/100000 to 41/100000 (p .001). No significant increase occurred in other groups. 33% of this increase is attributable to TB among persons with reported AIDS. The largest increases in male TB incidence occurred in 5 health districts with large populations of persons in AIDS risk groups: intravenous drug users in 4 health districts with a 55% increase; Haitian immigrants in 1 health district with a 59% increase. There is an ecological association between health districts with increasing TB rates and risk factor for AIDS. Serosurveys for evidence of HTLV-III/LAV infection among TB cases in these populations will help establish whether or not this relationship is causal. (full text)