Macroporous polystyrene-supported palladium catalyst containing a bulky N-heterocyclic carbene ligand for Suzuki reaction of aryl chlorides.
Macroporous polystyrene-supported palladium catalyst containing a bulky N-heterocyclic carbene ligand for Suzuki reaction of aryl chlorides.
复制标题
含有大体积 N-杂环卡宾配体的大孔聚苯乙烯负载钯催化剂，用于芳基氯的 Suzuki 反应。
作者：
Dong;Jong‐Ho Kim;Bong;Homan Kang;Juyoung Park;Yoon
以1-甲基咪唑为负载型N-杂环卡宾(NHC)前驱体固载钯催化剂，制备了大孔聚苯乙烯(MPS)负载1-介孔咪唑氯树脂。这种MPS负载的NHC前驱体很容易与Pd(OAc)2形成稳定的络合物，在室温下有效地催化了芳基碘和溴化物的Suzuki反应，在高温(100℃)下甚至催化了芳基氯的Suzuki反应。该催化剂在芳基溴的Suzuki反应中表现出良好的重复使用性。
Macroporous polystyrene (MPS)-supported 1-mesitylimidazolium chloride resin was prepared by reacting macroporous chloromethyl polystyrene with 1-mesitylimidazole as a supported N-heterocyclic carbene (NHC) precursor for the immobilization of a palladium catalyst. This MPS-supported NHC precursor readily formed a stable complex with Pd(OAc)2, which effectively catalyzed the Suzuki reaction of aryl iodide and bromides at room temperature and even aryl chlorides at elevated temperatures (100 degrees C). This catalyst showed reusability in the Suzuki reaction of aryl bromide.