Passive listening to preferred motor tempo modulates corticospinal excitability
Passive listening to preferred motor tempo modulates corticospinal excitability
复制标题
DOI：
10.3389/fnhum.2014.00252
复制
发表时间：
2014-04-24
影响因子：
2.9
通讯作者：
Thompson, James C.
中科院分区：
文献类型：
--
作者：
Michaelis, Kelly;Wiener, Martin;Thompson, James C.
节奏是我们生活的一个基本特征，大脑-运动耦合影响着各种行为。先前的研究已经表明，与运动系统处理相关的神经区域与感知节奏和旋律处理相耦合，使得对节奏刺激的感知可以引起运动系统的反应。然而，个人偏好调节运动系统的程度是未知的。最近的研究表明，被动地听韵律强节奏增加皮质脊髓兴奋性，如经颅磁刺激（TMS）所示。此外，这种效果是由高槽音乐，或音乐，激发运动，而神经影像学证据表明，运动前活动增加与节奏发生在一个首选的克里思（PT）类别。PT是指可以由自发运动克里思（SMT）和优选感知克里思（PPT）测量指示的假设的内源振荡器的速率。本研究调查是否听节奏在个人的PT优先调制运动系统的兴奋性。SMT是通过一项敲击任务在人类参与者中获得的，在该任务中，受试者被要求以他们最舒适的速率敲击响应键。受试者在11个对数间隔的节奏下听了一个10拍的音调序列，并对他们对每个节奏的偏好进行了评分（PPT）。我们发现SMT和PPT测量是相关的，表明首选和生产节奏发生在一个类似的速度。至关重要的是，单脉冲TMS提供给左M1在PPT的判断表明，皮质脊髓兴奋性，运动诱发电位（MEP）测量，调制的节奏更接近个人PT。然而，这种调节的具体性质在个体之间存在差异，一些人表现出PT周围兴奋性的增加，而另一些人则表现出减少。这些研究结果表明，由节律诱导的神经-运动耦合优先受以优选速率发生的节律调制，并且个体差异可以改变这种耦合的性质。
Rhythms are an essential characteristic of our lives, and auditory-motor coupling affects a variety of behaviors. Previous research has shown that the neural regions associated with motor system processing are coupled to perceptual rhythmic and melodic processing such that the perception of rhythmic stimuli can entrain motor system responses. However, the degree to which individual preference modulates the motor system is unknown. Recent work has shown that passively listening to metrically strong rhythms increases corticospinal excitability, as indicated by transcranial magnetic stimulation (TMS). Furthermore, this effect is modulated by high-groove music, or music that inspires movement, while neuroimaging evidence suggests that premotor activity increases with tempos occurring within a preferred tempo (PT) category. PT refers to the rate of a hypothetical endogenous oscillator that may be indicated by spontaneous motor tempo (SMT) and preferred perceptual tempo (PPT) measurements. The present study investigated whether listening to a rhythm at an individual's PT preferentially modulates motor system excitability. SMT was obtained in human participants through a tapping task in which subjects were asked to tap a response key at their most comfortable rate. Subjects listened a 10-beat tone sequence at 11 log-spaced tempos and rated their preference for each (PPT). We found that SMT and PPT measurements were correlated, indicating that preferred and produced tempos occurred at a similar rate. Crucially, single-pulse TMS delivered to left M1 during PPT judgments revealed that corticospinal excitability, measured by motor-evoked potentials (MEPs), was modulated by tempos traveling closer to individual PT. However, the specific nature of this modulation differed across individuals, with some exhibiting an increase in excitability around PT and others exhibiting a decrease. These findings suggest that auditory-motor coupling induced by rhythms is preferentially modulated by rhythms occurring at a preferred rate, and that individual differences can alter the nature of this coupling.