The postpartum uterus
The postpartum uterus
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DOI：
10.1016/j.cvfa.2004.06.008
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发表时间：
2004-11-01
影响因子：
4.1
通讯作者：
Sheldon, M
中科院分区：
文献类型：
--
作者：
Sheldon, M
奶牛是值得注意的国内物种中，几乎无处不在的细菌污染的子宫腔分娩后和临床子宫疾病的高发病率。这种子宫疾病不仅破坏子宫组织，而且通过扰动下丘脑、垂体和卵巢破坏卵泡的生长和功能。其他事件，如产后负能量平衡，也有类似的产后内分泌多层次的影响。卵巢周期性活动的恢复依赖于先天免疫系统解决子宫细菌污染，促进子宫复旧，以及短时间内达到负能量平衡最低点。虽然子宫疾病的危险因素已被描述，但预防策略并没有被广泛采用。因此，兽医必须有效地识别和治疗子宫疾病，以限制其对生育能力的负面影响。
The cow is notable among the domestic species for the almost ubiquitous bacterial contamination of the uterine lumen after parturition and the high incidence of clinical uterine disease. Such uterine disease not only disrupts uterine tissues, but also ovarian follicle growth and function by perturbation of the hypothalamus, pituitary, and ovary. Other events such as the postpartum negative energy balance also have similar multilevel effects on postpartum endocrinology. Return of ovarian cyclical activity is dependent on the innate immune system resolving uterine bacterial contamination, prompt uterine involution, and a short interval to the negative energy balance nadir. Although the risk factors for uterine disease have been described, preventive strategies are not widely adopted. Thus, veterinarians must identify and treat uterine disease efficiently to limit their negative effect on fertility.