Motor Learning in Children with Neurofibromatosis Type I
Motor Learning in Children with Neurofibromatosis Type I
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DOI：
10.1007/s12311-010-0217-2
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发表时间：
2011-03-01
期刊：
影响因子：
3.5
通讯作者：
van der Geest, Josef N.
中科院分区：
文献类型：
--
作者：
Krab, Lianne C.;de Goede-Bolder, Arja;van der Geest, Josef N.
这项研究的目的是使用三项关于运动表现和运动学习的任务来量化在1型神经纤维瘤病(NF1)中经常观察到的运动控制问题。将70名患有NF1的儿童与年龄匹配的对照组进行比较。正如预期的那样，NF1儿童在视觉-运动整合(Beery VMI)方面显示出严重的问题。棱镜诱导的手部运动适应性似乎受到轻微影响。然而，没有观察到简单的眼睛或手运动的准确性有明显的损害。此外，眼球跳动适应，一种小脑依赖的任务，似乎是正常的。这些结果表明，NF1儿童在日常生活中的运动问题不太可能仅仅源于运动学习的障碍。因此，我们的发现不支持NF1儿童的小脑普遍功能障碍。
The aim of this study was to quantify the frequently observed problems in motor control in Neurofibromatosis type 1 (NF1) using three tasks on motor performance and motor learning. A group of 70 children with NF1 was compared to age-matched controls. As expected, NF1 children showed substantial problems in visuo-motor integration (Beery VMI). Prism-induced hand movement adaptation seemed to be mildly affected. However, no significant impairments in the accuracy of simple eye or hand movements were observed. Also, saccadic eye movement adaptation, a cerebellum dependent task, appeared normal. These results suggest that the motor problems of children with NF1 in daily life are unlikely to originate solely from impairments in motor learning. Our findings, therefore, do not support a general dysfunction of the cerebellum in children with NF1.