UNCERTAINTIES IN DOSES DUE TO THE NUMBER OF AEROSOL PARTICLES: STUDY ON 239PuO2 USING DEFAULT PARAMETERS FOR WORKERS
UNCERTAINTIES IN DOSES DUE TO THE NUMBER OF AEROSOL PARTICLES: STUDY ON 239PuO2 USING DEFAULT PARAMETERS FOR WORKERS
复制标题
气溶胶颗粒数量引起的剂量不确定性：使用工作人员默认参数对 239PuO2 进行研究
DOI：
10.1097/00004032-200410000-00009
复制
发表时间：
2004
期刊：
影响因子：
2.2
通讯作者：
P. Fritsch
中科院分区：
文献类型：
--
作者：
P. Fritsch
个别颗粒的行为已被考虑到估计，吸入后，沉积分数和剂量的不确定性，由于239PuO2气溶胶颗粒的数量。使用ICRP模型和为工作人员推荐的默认参数，经过计算和模拟暴露于500至3 × 106粒子（约1 Bq至6 kBq）后，获得了类似的结果。从模拟中获得的不均匀性随着粒子数量的减少而增加。在接触不到1 × 105个粒子的情况下通常不会出现存款的隔离区，观察到沉积分数的最大不确定性。在隔离区和淋巴结中观察到了50年来核衰变数量的类似巨大不确定性。对于给定数量的粒子，承诺等效剂量的不确定性从胸外区域到淋巴结、支气管、细支气管和肺泡上皮逐渐降低。对于1 × 104个粒子，肺、肝、骨表面、红骨髓和性腺的承诺等效剂量以及单位摄入剂量（DPUI）观察到类似的不确定性，而对于1 × 105个粒子及以上，DPUI的不确定性高于等效剂量。解释是，在某些模拟中，最大承诺等效剂量被输送到胸外呼吸道区域（在这种情况下，必须更改DPUI计算模式）。
The behavior of individual particles has been taken into account to estimate, after inhalation, uncertainties in deposition fractions and doses due to the number of 239PuO2 aerosol particles. Using ICRP models and default parameters recommended for workers, similar results were obtained after calculation and after simulations of exposures to 500 to 3 × 106 particles (from about 1 Bq to 6 kBq). Uncertainties obtained from simulations increase as the number of particles decreases. The maximal uncertainties in the deposition fraction were observed for the sequestered regions in which no deposit often occurs for exposures of less than 1 × 105 particles. Similar large uncertainties in the number of nuclear disintegrations over 50 years were observed in the sequestered regions as well as in lymph nodes. For a given number of particles, uncertainties in committed equivalent doses gradually decrease from the extra-thoracic region to lymph nodes, bronchi, bronchioles, and alveolar interstitium. For 1 × 104 particles, similar uncertainties were observed for the committed equivalent doses delivered to lung, liver, bone surfaces, red marrow and gonads, and for dose per unit intake (DPUI), whereas for 1 × 105 particles and more, uncertainties in DPUI were higher than those in equivalent doses. The explanation is that in some simulations the maximal committed equivalent dose was delivered to the extra-thoracic respiratory tract region (in which case the DPUI calculation mode must be changed).