Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor

Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor
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Cas9 不具有核酸外切酶活性,可导致交错切割和突出端,以及无需模板供体即可预测的二核苷酸和三核苷酸 CRISPR 插入

DOI:
10.1038/s41421-019-0120-z
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发表时间:
2019-10
期刊:
影响因子:
33.5
通讯作者:
Wu Qiang
Wu Qiang
中科院分区:
生物学1区
文献类型:
--
作者:
Shi Xin;Shou Jia;Mehryar Mohammadreza M.;Li Jingwei;Wang Leyang;Zhang Mo;Huang Haiyan;Sun Xiaofang;Wu Qiang

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