Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor
Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor
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Cas9 不具有核酸外切酶活性,可导致交错切割和突出端,以及无需模板供体即可预测的二核苷酸和三核苷酸 CRISPR 插入
DOI:
10.1038/s41421-019-0120-z
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发表时间:
2019-10
期刊:
影响因子:
33.5
通讯作者:
Wu Qiang
中科院分区:
文献类型:
--
作者:
Shi Xin;Shou Jia;Mehryar Mohammadreza M.;Li Jingwei;Wang Leyang;Zhang Mo;Huang Haiyan;Sun Xiaofang;Wu Qiang
Dear Editor, Genome editing has found applications in almost every field in biology and medicine and has permeated many aspects of our society. In particular, the clustered regularly interspaced short palindromic repeats (CRISPR)— CRISPR-associated nuclea
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影响因子:
12.3
作者:
Guo T;Feng YL;Xiao JJ;Liu Q;Sun XN;Xiang JF;Kong N;Liu SC;Chen GQ;Wang Y;Dong MM;Cai Z;Lin H;Cai XJ;Xie AY
通讯作者:
Xie AY
影响因子:
56.9
作者:
Wienert, Beeke;Wyman, Stacia K.;Corn, Jacob E.
通讯作者:
Corn, Jacob E.
影响因子:
64.8
作者:
Shen MW;Arbab M;Hsu JY;Worstell D;Culbertson SJ;Krabbe O;Cassa CA;Liu DR;Gifford DK;Sherwood RI
通讯作者:
Sherwood RI
影响因子:
20.6
作者:
Long C
通讯作者:
Long C
DOI:
10.1073/pnas.1716855115
发表时间:
2018-02-27
影响因子:
11.1
作者:
Lemos, Brenda R.;Kaplan, Adam C.;Haber, James E.
通讯作者:
Haber, James E.