A water-soluble conjugated polymer with azobenzol side chains based on "turn-on" effect for hypoxic cell imaging
A water-soluble conjugated polymer with azobenzol side chains based on "turn-on" effect for hypoxic cell imaging
复制标题
基于“开启”效应的具有偶氮苯侧链的水溶性共轭聚合物用于缺氧细胞成像
DOI：
10.1039/c6py01567k
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发表时间：
2016-01-01
影响因子：
4.6
通讯作者：
Huang, Wei
中科院分区：
文献类型：
--
作者：
Li, Jie;Yuan, Yan;Huang, Wei
报道了一种用于缺氧成像的具有酶可裂解连接（偶氮苯）侧链的水溶性共轭聚合物（WSCP）。聚合物的荧光将随着偶氮苯部分在缺氧中裂解而恢复。这种共轭聚合物被证明是一种良好的缺氧传感器。
A water-soluble conjugated polymer (WSCP) with enzymatic cleavable linkages (azobenzene) side chains for hypoxia imaging is reported. The fluorescence of the polymer would be recovered as the azobenzene moieties cleaved in hypoxia. This conjugated polymer was proved to be a good hypoxic sensor.