Genotoxic substances in the St. Lawrence system I: Industrial genotoxins sorbed to particulate matter in the St. Lawrence, St. Maurice, and Saguenay rivers, Canada
Genotoxic substances in the St. Lawrence system I: Industrial genotoxins sorbed to particulate matter in the St. Lawrence, St. Maurice, and Saguenay rivers, Canada
复制标题
圣劳伦斯系统中的基因毒性物质 I：加拿大圣劳伦斯河、圣莫里斯河和萨格奈河中颗粒物吸附的工业基因毒素
DOI：
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
C. Blaise
中科院分区：
文献类型：
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作者：
P. White;J. Rasmussen;C. Blaise
Previous investigations of organic genotoxins in industrial effluents discharged into the St. Lawrence Rivers system (Quebec, Canada) indicated that a substantial fraction of the genotoxicity is adsorbed to suspended particulate matter. This study used the SOS Chromotest to investigate the presence, potency, and behavior of particle‐bound genotoxins in the downstream ecosystem. The results indicate that although extracts of both suspended and sedimented particulate matter are genotoxic, suspended particulate matter samples are more potent in the absence of S9 activation, with the reverse being true for bottom sediments. The results confirmed a positive relationship between the genotoxicity of bottom sediment extracts and sediment organic matter content. A similar relationship between organic matter content and total polycyclic aromatic hydrocarbon (PAH) concentration indicates that putative genotoxins have physicochemical properties similar to the PAH class of contaminants. Conversion of PAH values to benzo[a]pyrene equivalents indicates that measured PAHs only account for a small fraction (∼10%) of the observed SOS Chromotest response. Sites that receive discharges from foundries, aluminum refineries, and petroleum refineries yielded several of the most genotoxic samples. Further analyses revealed that the genotoxicity of suspended and sedimented particulate matter extracts is empirically related to the genotoxicity of industrial discharges. Comparisons of total genotoxicity levels in suspended particulates and bottom sediments suggest that direct‐acting substances adsorbed to suspended matter are rapidly degraded and/or converted to more stable progenotoxins upon deposition. Further research is required to test this hypothesis and investigate effects on indigenous biota.
大肠杆菌和沙门氏菌致突变性中的 SOS 诱导：使用 330 种化合物进行比较。
影响因子：
2.7
作者：
Mersch-Sundermann,V;Schneider,U;Klopman,G;Rosenkranz,HS
通讯作者：
Rosenkranz,HS