CAMPYLOBACTER-PYLORI AND PEPTIC-ULCER DISEASE
CAMPYLOBACTER-PYLORI AND PEPTIC-ULCER DISEASE
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DOI:
10.1016/s0016-5085(89)80057-5
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发表时间:
1989-02-01
期刊:
影响因子:
29.4
通讯作者:
GRAHAM, DY
中科院分区:
文献类型:
--
作者:
GRAHAM, DY
Campylobacter pyloriis now known to be the most common and important cause of gastritis, andC. pyloriinfections have been associated with duodenal ulcer, gastric ulcer, nonulcer dyspepsia, and gastric cancer. Although it has been only possible to cultureC. pylorifor about 5 yr, there are already sufficient data available to allow us to develop the basic framework that relatesC. pylorigastritis to the causation of peptic ulcer disease. We review the data and propose mechanisms that implicateC. pylorias an important factor in the pathogenesis of peptic ulcer disease and consider the therapeutic implications. What we now know aboutC. pyloribegins to unravel some of the mysteries surrounding peptic ulcer disease.