The regioselective Larock indole synthesis catalyzed by NHC-palladium complexes
The regioselective Larock indole synthesis catalyzed by NHC-palladium complexes
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DOI：
10.1039/c3ra42788a
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发表时间：
2013-01-01
期刊：
影响因子：
3.9
通讯作者：
Pang, Guangsheng
中科院分区：
文献类型：
--
作者：
He, Pan;Du, Yufeng;Pang, Guangsheng
首次开发了二茂铁功能化的N-杂环卡宾（NHC）-钯配合物催化邻碘苯胺或邻溴苯胺及其衍生物与对称和不对称内炔反应合成2，3-二取代吲哚的实用和区域选择性的方法，并以较高的产率和区域选择性分离了吲哚。
The first practical and regioselective process for the synthesis of 2,3-disubstituted indoles from the reaction of o-iodoanilines or o-bromoanilines and their derivatives with symmetrical and unsymmetrical internal alkynes catalyzed by a ferrocene-functionalized N-heterocyclic carbene (NHC)-palladium complex has been developed, and the indoles were isolated in good yields with high regioselectivity.