Nearest-neighbor distance of intermediate filaments in axons and schwann cells
Nearest-neighbor distance of intermediate filaments in axons and schwann cells
复制标题
轴突和雪旺细胞中中间丝的最近邻距离
作者：
K. Tohyama;C. Idé;T. Nitatori;R. Yokota
为了区分失神经支配和再神经支配的周围神经中的轴突和雪旺细胞突起，测量了失神经支配和随后再生的周围神经的轴突和雪旺细胞中的中间丝的最近邻距离（NND）。结果表明，再生轴突的NND明显增大（41.9±14.1）nm（再生组23.1±7.1 nm，去神经组19.7±5.8 nm）。很明显，在所有情况下，轴突中的NND（29.0-41.9 nm）大于雪旺细胞中的NND（19.7-23.1 nm）。因此，通常可以认为轴突中的NND比雪旺细胞中的NND大。这一事实可用于区分轴突和许旺细胞突起，当后者具有与前者类似的轮廓时，如在Büngner带和再生神经中。
SummaryTo distinguish axons from Schwann cell processes in the denervated (Büngner's bands) and reinnervated peripheral nerves, the nearest-neighbor distance of intermediate filaments (NND) was measured in axons and Schwann cells from denervated and subsequent regenerating peripheral nerves. It was revealed that the NND was much larger in regenerating axons (41.9±14.1 nm) than in Schwann cell processes (23.1±7.1 nm in regeneration and 19.7±5.8 nm in denervation).In addition, the NND was also measured in the normal adult and developing peripheral nerves, and it became clear that in all cases the NND in axons (29.0–41.9 nm) was larger than in Schwann cells (19.7–23.1 nm). Thus, it can be generally considered that the NND is larger in axons than in Schwann cells. This fact can be used for the distinction between axons and Schwann cell processes, when the latter have a profile similar to that of the former as in Büngner's bands and in the regenerating nerves.