ACOUSTIC REFLECTOMETRY FOR AIRWAY MEASUREMENTS IN MAN - IMPLEMENTATION AND VALIDATION

ACOUSTIC REFLECTOMETRY FOR AIRWAY MEASUREMENTS IN MAN - IMPLEMENTATION AND VALIDATION
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DOI:
10.1088/0967-3334/14/2/007
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发表时间:
1993-05-01
影响因子:
3.2
通讯作者:
DOUGLAS, NJ
DOUGLAS, NJ
中科院分区:
工程技术3区
文献类型:
--
作者:
MARSHALL, I;MARAN, NJ;DOUGLAS, NJ

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一个实际的实施声反射测定法确定气道面积在常规临床使用。与以前的系统相比,它的进步包括便携性、测量期间的自由呼吸、不需要用氦/氧平衡以及实时显示气道面积。用气道模型对反射计进行的验证给出了在5- 10%范围内的准确度和再现性(变异系数(CV))。在人类志愿者中,运行内CV通常为10%,日常CV为20%。证明了呼吸方式对气道面积的影响。在十名正常志愿者中,比较了评估咽部和声门区域的声学和磁共振成像(MRI)方法。口咽部的结果(平均值+/-SD)声学测量为1.0+/-0.3 cm 2,MRI测量为0.9+/-0.5 cm 2(p=0.77)。声门面积的相应数值为1.3+/-0.3 cm 2和1.1+/-0.4 cm 2(p=0.09)。
A practical implementation of acoustic reflectometry for determining airway areas in routine clinical use is described. Advances over previous systems include portability, free breathing during measurements, no need to equilibrate with helium/oxygen, and real-time display of airway areas. Validation of the reflectometer with an airway model gave accuracies and reproducibilities (coefficient of variation (cv)) in the range 5-10%. With human volunteers, the within-run cv was typically 10%, and the day-to-day cv was 20%. The effect of breathing pattern on airway areas is demonstrated.In ten normal volunteers, acoustic and magnetic resonance imaging (MRI) methods of assessing pharyngeal and glottal areas were compared. The results (mean+/-SD) for the oropharynx were 1.0+/-0.3 cm2 acoustically and 0.9+/-0.5cm2 by MRI (p=0.77). The corresponding figures for glottal areas were 1.3+/-0.3 cm2 and 1.1+/-0.4 cm2 (p=0.09).