Continuous intraocular pressure monitoring with a wireless ocular telemetry sensor: initial clinical experience in patients with open angle glaucoma

Continuous intraocular pressure monitoring with a wireless ocular telemetry sensor: initial clinical experience in patients with open angle glaucoma
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DOI:
10.1136/bjo.2010.192922
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发表时间:
2011-05-01
影响因子:
4.1
通讯作者:
Shaarawy, Tarek
Shaarawy, Tarek
中科院分区:
医学2区
文献类型:
--
作者:
Mansouri, Kaweh;Shaarawy, Tarek

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作者报告了他们使用一种新型的无线眼遥测传感器(OTS) (Sensimed AG,瑞士)在开角型青光眼患者中持续监测眼压(IOP)的初步临床结果。这是一个前瞻性的、观察性的队列研究,共有15名患者。OTS是一种内置微机电系统的一次性硅胶隐形眼镜,可测量眼压变化引起的角膜曲率变化。安装在眼睛周围的天线接收数据,然后将数据传输到记录器。所有患者均有信号记录。13例(87%)患者完成了24小时IOP监测:1例患者由于设备不耐受而停止IOP监测,另1例患者由于技术设备故障而获得不完整的IOP记录。在9/13(69%)患者中,最高信号记录在夜间。无严重不良事件记录。OTS在24小时内监测患者IOP波动方面显示出良好的安全性和功能性。这项技术有可能提供迄今为止无法获得的IOP时间生物学数据,可能会改善青光眼患者的护理。
The authors report their initial clinical results with a novel wireless ocular telemetry sensor (OTS) (Sensimed AG, Switzerland) for continuous intraocular pressure (IOP) monitoring in patients with open angle glaucoma. This was a prospective, observational cohort of 15 patients. The OTS is a disposable silicone contact lens with an embedded micro-electromechanical system, which measures changes in corneal curvature induced by variations in IOP. An antenna, mounted around the eye, receives the data, which are then transmitted to a recorder. A signal was recorded in all patients. Thirteen (87%) patients completed 24-h IOP monitoring: one patient discontinued IOP monitoring due to device intolerance, and incomplete recordings were obtained in a second patient due to technical device malfunction. In 9/13 (69%) patients, the highest signals were recorded during the nocturnal period. No serious adverse events were recorded. The OTS shows good safety and functionality to monitor IOP fluctuations in patients over 24 h. This technology has the potential to provide hitherto unobtainable data on the chronobiology of IOP, possibly leading to improved care of glaucoma patients.