Symbiotic Properties of Antibiotic-Resistant and Auxotrophic Mutants of Rhizobium leguminosarum
Symbiotic Properties of Antibiotic-Resistant and Auxotrophic Mutants of Rhizobium leguminosarum
复制标题
豆根瘤菌抗生素抗性和营养缺陷型突变体的共生特性
DOI：
10.1111/j.1365-2672.1979.tb01169.x
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发表时间：
1979
影响因子：
4
通讯作者：
A. Pain
中科院分区：
文献类型：
--
作者：
A. Pain
从豆科根瘤菌中分离到一批营养缺陷型和抗根瘤菌的突变株，并对其共生特性进行了研究。在测试的营养缺陷型突变体中，仅发现具有腺嘌呤需求的那些是共生缺陷的，并且这些都是非感染性的。在分离出的抗利福平突变体中，只有少数抗利福平突变体具有改良的共生表型，这是无效的。初步证据表明，在这些突变体的耐药性的基础是一个修改的DNA依赖的RNA聚合酶。
A number of auxotrophic and antibiotic-resistant mutants of Rhizobium leguminosarum were isolated and their symbiotic properties examined. Among the auxotrophic mutants tested, only those with an adenine requirement were found to be symbiotically defective and these were all non-infective. Of the antibiotic-resistant mutants isolated, only a minority of the rifampicin-resistant mutants had a modified symbiotic phenotype and this was ineffective. Preliminary evidence suggests that the basis for the resistance in these mutants is a modified DNA-dependent RNA polymerase.