Comparison of two zoonotic viruses from the order &ITBunyavirales&IT
Comparison of two zoonotic viruses from the order &ITBunyavirales&IT
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DOI：
10.1016/j.coviro.2017.10.007
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发表时间：
2017-12-01
影响因子：
5.9
通讯作者：
Wilson, William C.
中科院分区：
文献类型：
--
作者：
Noronha, Leela E.;Wilson, William C.
对两种地理上不同的布尼亚病毒目病毒进行了比较，这两种病毒是人畜共患病的，已知会导致反刍动物的先天性异常。其中一种病毒，缓存谷热病毒，在美洲发现，主要与绵羊的疾病有关。另一种是裂谷热病毒，发现于撒哈拉以南非洲，与骆驼、牛、山羊和绵羊的疾病有关。到目前为止，这两种病毒都与人类的致畸性有关。简要回顾了这两种病毒，并讨论了潜在的基因变化，特别是如果引入可能影响致病性的新生态。
A comparison of two geographicallly distinct viruses in the order Bunyavirales that are zoonotic and known to cause congenital abnormalities in ruminant livestock was performed. One of these viruses, Cache Valley fever virus, is found in the Americas and is primarily associated with disease in sheep. The other, Rift Valley fever virus, is found in Sub-Saharan Africa and is associated with disease in camels, cattle, goats and sheep. Neither virus has been associated with teratogenicity in humans to date. These two viruses are briefly reviewed and potential for genetic changes especially if introduced into new ecology that could affect pathogenicity are discussed.