Prognostic nomogram based on the metastatic lymph node ratio for gastric neuroendocrine tumour: SEER database analysis
Prognostic nomogram based on the metastatic lymph node ratio for gastric neuroendocrine tumour: SEER database analysis
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DOI：
10.1136/esmoopen-2019-000632
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发表时间：
2020-03-01
期刊：
影响因子：
7.3
通讯作者：
Wu, Junxin
中科院分区：
文献类型：
--
作者：
Li, Jinluan;Lin, Yaobin;Wu, Junxin
目的 胃神经内分泌肿瘤（g-NETs）的生存预测存在争议。探讨转移淋巴结比率（LNR）对g-NET患者预后的影响，并绘制列线图来预测患者的生存率。方法在监测、流行病学和最终结果数据库的基础上进行纵向研究。通过使用 Pearson 相关和 Cox 回归研究 LNR 与生存之间的关联。借助列线图预测总生存率（OS）和癌症特异性生存率（CSS）。结果本研究共纳入了2004年至2015年诊断的315例g-NET患者。 LNR被发现与OS和CSS呈负相关（Pearson相关系数：0.343（p
Objective The prediction of survival of gastric neuroendocrine tumours (g-NETs) is controversial. Prognostic effects of the metastatic lymph node ratio (LNR) in patients with g-NET were explored, and a nomogram was plotted to predict the survival rates of patients.Methods A longitudinal study conducted on the basis of the Surveillance, Epidemiology, and End Results database. The association between LNR and survival were investigated by using Pearson correlation and Cox regression. Overall survival (OS) and cancer-specific survival (CSS) rates were predicted with the help of nomograms.Results A total of 315 patients with g-NET diagnosed from 2004 to 2015 were included in this study. LNR was discovered to have a negative correlation with OS and CSS (Pearson correlation coefficients: 0.343 (p