POST-TETANIC POTENTIATION OF RESPONSE IN MONOSYNAPTIC REFLEX PATHWAYS OF THE SPINAL CORD
POST-TETANIC POTENTIATION OF RESPONSE IN MONOSYNAPTIC REFLEX PATHWAYS OF THE SPINAL CORD
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DOI：
10.1085/jgp.33.2.147
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发表时间：
1949-01-01
影响因子：
3.8
通讯作者：
LLOYD, DPC
中科院分区：
文献类型：
--
作者：
LLOYD, DPC
After tetanic afferent stimulation of a monosynaptic reflex pathway transmission through that pathway of isolated reflex volleys is enhanced for some minutes. Post-tetanic potentiation occurs in both extensor and flexor monosynaptic reflex arcs, but little post-tetanic change attends transmission through plurisynaptic reflex arcs. Facilitator and inhibitor actions of monosynaptic reflex afferent fibers, as well as the transmitter action, are potentiated following tetanization. A var. of tests shows that the potentiating influence of a tetanus is limited to subsequent action on the part of the tetanized fibers themselves. Direct measurement of afferent volleys shows them to be increased, apparently the result of post-tetanic hyperpolari-zation (positive after-potential). The augmented impulses provide a more intense synaptic action. Post-tetanic potentiation and after-discharge are unrelated phenomena.
