NATIONAL CANCER DATABASE REPORT ON CANCER OF THE HEAD AND NECK: 10-YEAR UPDATE
NATIONAL CANCER DATABASE REPORT ON CANCER OF THE HEAD AND NECK: 10-YEAR UPDATE
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DOI：
10.1002/hed.21022
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发表时间：
2009-06-01
影响因子：
2.9
通讯作者：
Langer, Corey J.
中科院分区：
文献类型：
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作者：
Cooper, Jay S.;Porter, Kim;Langer, Corey J.
背景我们试图研究美国头颈部肿瘤的癌症护理现状。因此，我们对1990年至2004年国家癌症数据库（NCDB）中包含的约822，000例头颈癌病例进行了回顾性纵向研究，约占美国估计事件诊断的75%。方法。回顾了在此期间诊断并报告给NCDB的所有头颈部癌症病例，并按疾病和宿主因素分组进行描述性统计分析，并与10年前进行的类似分析进行比较。尽管存在许多相似之处，但头颈癌发生了几个重大变化，最值得注意的是（1）患有粘膜来源的鳞状细胞癌的老年患者的数量减少，同时患有甲状腺来源的腺癌的老年患者的数量增加，和（2）减少单纯使用放射治疗进行治疗，有利于化疗加强放射治疗。头颈部癌症包括一组异质性肿瘤，其精确组成随时间而变化，其治疗也随之演变。NCDB非常适合捕捉这些信息，并提供对头颈部肿瘤癌症护理现状的分析和随时间推移的纵向视图。(c)2009 Wiley Periodicals，Inc.头颈部31：748 - 758，2009年
Background. We sought to examine the current state of cancer care for head and neck tumors in the United States. We therefore performed a retrospective, longitudinal study of the approximately 822,000 head and neck cancer cases included in the National Cancer Data Base (NCDB) for 1990 through 2004, representing approximately 75% of the estimated incident diagnoses in the United States.Methods. All cases of head and neck cancer diagnosed and reported to the NCDB during this interval were reviewed, and descriptive statistics, grouped by disease and host factors, were analyzed over time and compared with a prior similar analysis done 10 years ago.Results. Although many similarities persist, several major changes in head and neck cancer have occurred, most notably (1) a decrease in the number of the older-aged patients who have mucosally derived squamous cell carcinomas coupled with an increase in the number of younger-aged patients who have thyroid-origin adenocarcinomas and (2) a decrease in the use of radiation therapy alone for treatment in favor of chemotherapy enhanced radiation therapy.Conclusion. Head and neck cancers include a heterogeneous group of tumors whose precise composition changes over time and whose therapy evolves as well. The NCDB is well suited to capture this information and provide both an analysis of the current state of cancer care for head and neck tumors and a longitudinal view over time. (c) 2009 Wiley Periodicals, Inc. Head Neck 31: 748-758, 2009