Causal links between parietal alpha activity and spatial auditory attention
Causal links between parietal alpha activity and spatial auditory attention
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DOI：
10.7554/elife.51184
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发表时间：
2019-11-29
期刊：
影响因子：
7.7
通讯作者：
Shinn-Cunningham, Barbara G.
中科院分区：
文献类型：
--
作者：
Deng, Yuqi;Reinhart, Robert M. G.;Shinn-Cunningham, Barbara G.
视觉和听觉空间选择性注意都会导致顶叶皮质阿尔法(8-14赫兹)振荡功率的偏侧化：阿尔法在注意焦点同侧半球增加。脑刺激研究表明，顶叶阿尔法与对侧视觉空间表征的抑制之间存在因果关系。然而，没有证据表明顶叶阿尔法控制听觉空间注意力。在这里，我们对执行听觉任务的受试者进行了高清晰度经颅交流电刺激(HD-TAC)，在这项任务中，他们根据空间或非空间特征来引导注意力。右侧顶叶皮质的α(10 Hz)而不是theta(6 Hz)HD-Tacs干扰了左侧听觉空间，但不干扰右侧听觉空间。顶叶刺激对非空间听觉注意没有影响。此外，刺激后试验的表现迅速恢复到基线水平。这些结果表明，顶叶阿尔法脑刺激对听觉空间注意的自上而下控制具有因果、频率、半球和任务特异性的效应。
Both visual and auditory spatial selective attention result in lateralized alpha (8-14 Hz) oscillatory power in parietal cortex: alpha increases in the hemisphere ipsilateral to attentional focus. Brain stimulation studies suggest a causal relationship between parietal alpha and suppression of the representation of contralateral visual space. However, there is no evidence that parietal alpha controls auditory spatial attention. Here, we performed high definition transcranial alternating current stimulation (HD-tACS) on human subjects performing an auditory task in which they directed attention based on either spatial or nonspatial features. Alpha (10 Hz) but not theta (6 Hz) HD-tACS of right parietal cortex interfered with attending left but not right auditory space. Parietal stimulation had no effect for nonspatial auditory attention. Moreover, performance in post-stimulation trials returned rapidly to baseline. These results demonstrate a causal, frequency-, hemispheric-, and task-specific effect of parietal alpha brain stimulation on top-down control of auditory spatial attention.