Assessment of the hepatic arterial and portal venous blood flows during pregnancy with Doppler ultrasonography
Assessment of the hepatic arterial and portal venous blood flows during pregnancy with Doppler ultrasonography
复制标题
DOI：
10.1007/pl00007495
复制
发表时间：
2002-01-01
影响因子：
2.6
通讯作者：
Araki, T.
中科院分区：
文献类型：
--
作者：
Nakai, A.;Sekiya, I.;Araki, T.
目的：本研究的目的是评估是否双肝血供改变健康孕妇与非孕妇相比。材料与方法：应用多普勒超声技术对67例孕10-40周的健康孕妇和22例非孕妇女的肝总动脉和门静脉血流进行了检测。结果如下：在非妊娠组中，平均（SD）肝动脉血流量、门静脉血流量和总肝血流量分别为0.57（0.31）L/min、1.25（0.46）L/min和1.82（0.63）L/min。健康妊娠组孕28周后门静脉血流量和肝总血流量明显增加。然而，肝动脉血流在妊娠期间保持不变。肝动脉血流量与门静脉血流量无相关性。结论：妊娠晚期肝脏灌注较非妊娠期增加。由于肝动脉血流在妊娠期间保持不变，肝灌注增加的主要决定因素是门静脉回流。这些数据表明，肝动脉和门静脉血管领土的监管机制，允许独立的变化在怀孕期间。
Purpose: The aim of this study was to evaluate whether the dual hepatic blood supply is altered in healthy pregnant women compared with that in non-pregnant women. Materials and methods: Flow waveforms in common hepatic artery and portal vein were obtained in 67 healthy pregnant women at 10-40 weeks gestation and 22 nonpregnant women by using Doppler ultrasonography. Results: In the nonpregnant group, the mean (SD) hepatic arterial blood flow, portal venous blood flow, and total liver blood flow were 0.57 (0.31) L/min, 1.25 (0.46) L/min, and 1.82 (0.63) L/min, respectively. In the healthy pregnant group, the portal venous blood flow and total liver blood flow significantly increased after 28 weeks gestation. However, the hepatic arterial blood flow remained unchanged during pregnancy. There was no relationship between the hepatic arterial blood flow and the portal venous blood flow. Conclusion: The results demonstrated that the hepatic perfusion increased during third trimester compared to nonpregnant level. Because the hepatic arterial blood flow remained unchanged during pregnancy, major determinant of the increase in the hepatic perfusion was the portal venous return. The data suggest that the hepatic arterial and portal venous vascular territories have regulatory mechanisms that allow for independent changes during pregnancy.