Risk of large-for-gestational-age newborns in women with gestational diabetes by race and ethnicity and body mass index categories.
Risk of large-for-gestational-age newborns in women with gestational diabetes by race and ethnicity and body mass index categories.
复制标题
按种族和体重指数类别划分的妊娠期糖尿病女性生下大于胎龄新生儿的风险。
DOI：
10.1097/aog.0b013e318291b15c
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发表时间：
2013
影响因子：
7.2
通讯作者：
Hedderson,MoniqueM
中科院分区：
文献类型：
--
作者：
Sridhar,SnehaB;Ferrara,Assiamira;Ehrlich,SamanthaF;Brown,SusanD;Hedderson,MoniqueM
目的：比较五个种族和民族中体重指数（BMI）各类别的大胎龄（LGA）新生儿的患病率。方法：本队列研究检查了1995年至2006年在北方加州凯撒医疗机构分娩的7,468名妊娠期糖尿病（GDM）妇女。人种和种族组为非西班牙裔白色、非裔美国人、西班牙裔、亚裔和菲律宾人。使用世界卫生组织国际指南对BMI进行分类（正常，18.50-24.99;超重，25.00-29.99;肥胖，30.00-34.99;肥胖II级，35.00或更高）。LGA新生儿定义为出生体重超过研究人群种族或民族和胎龄的第90百分位数-特定出生体重分布。Logistic回归被用来估计有LGA新生儿的BMI和种族和ethnication.RESULTS的几率：LGA新生儿的总体患病率最高的非洲裔美国妇女（25.1%），最低的亚洲人（13.9%），和中间的西班牙裔（17.3%），白色（16.4%）和菲律宾妇女（15.3%）。LGA新生儿的风险增加最高的II类肥胖的妇女在大多数种族和民族群体中观察到，和非洲裔美国人和亚洲妇女II类肥胖的LGA新生儿的风险增加了四倍，与正常体重的妇女在同一种族和ethnic group.CONCLUSIONS：非洲裔美国妇女GDM有更大的风险LGA新生儿在较低的BMI比其他种族和民族。临床医生应该意识到，在GDM的妇女，可能有显着的种族和民族差异的风险LGA新生儿BMI thresholds.Level的证据：IIR-N和种族差异存在的风险大的胎龄新生儿的体重指数阈值之间的母亲妊娠糖尿病。
OBJECTIVE:To compare the prevalence of large-for-gestational-age (LGA) newborns across categories of body mass index (BMI) in five racial and ethnic groups.METHODS:This cohort study examined 7,468 women with gestational diabetes mellitus (GDM) who delivered a live newborn between 1995 and 2006 at Kaiser Permanente Northern California. The racial and ethnic groups were non-Hispanic white, African American, Hispanic, Asian, and Filipina. The BMI was classified using the World Health Organization International guidelines (normal, 18.50–24.99; overweight, 25.00–29.99; obese, 30.00–34.99; obese class II, 35.00 or higher). Having an LGA newborn was defined as birth weight more than 90th percentile for the study population's race or ethnicity and gestational age--specific birth weight distribution. Logistic regression was used to estimate odds of having an LGA newborn by BMI and race and ethnicity.RESULTS:Overall prevalence of LGA newborns was highest in African American women (25.1%), lowest in Asians (13.9%), and intermediate among Hispanic (17.3%), white (16.4%), and Filipina women (15.3%). The highest increased risk of LGA newborns was observed among women with class II obesity in most racial and ethnic groups, and African American and Asian women with class II obesity had a four-fold increased risk of LGA newborns compared with women of normal weight in the same racial and ethnic group.CONCLUSIONS:African American women with GDM have a greater risk of LGA newborns at a lower BMI than other racial and ethnic groups. Clinicians should be aware that among women with GDM, there may be significant racial and ethnic differences in the risk of LGA newborns by BMI threshold.LEVEL OF EVIDENCE:IIRacial and ethnic differences exist in risk of large-for-gestational-age newborns by body mass index threshold among mothers with gestational diabetes.