Attenuation of auditory N1 results from identity-specific action-effect prediction
Attenuation of auditory N1 results from identity-specific action-effect prediction
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DOI：
10.1111/ejn.12120
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发表时间：
2013-04-01
影响因子：
3.4
通讯作者：
Waszak, Florian
中科院分区：
文献类型：
--
作者：
Hughes, Gethin;Desantis, Andrea;Waszak, Florian
听觉N1事件相关电位先前已被观察到在人类行为触发的音调中减弱。这种衰减被认为是由运动预测机制产生的，并且被认为对代理归因很重要。本研究旨在严格检验基于动作预测的感觉衰减的概念。在每次试验中，参与者要执行四种自愿行动中的一种，每个按钮都与可预测或不可预测的行动效果相关联。此外，每只手的动作可能导致与特定手的预测一致或不一致的动作效果。我们观察到N1振幅在可预测音调和不可预测音调之间没有显著差异。当对比与手部特定预测一致或不一致的动作效应时，我们观察到与预测不一致的动作效应相比，预测一致的动作效应显著衰减。这些新发现表明，准确的动作效应预测驱动听觉刺激的感觉衰减。这些发现对于理解动作效应预测和感觉衰减的机制具有重要意义，并可能对研究精神分裂症的动作意识和代理具有临床意义。
The auditory N1 event-related potential has previously been observed to be attenuated for tones that are triggered by human actions. This attenuation is thought to be generated by motor prediction mechanisms and is considered to be important for agency attribution. The present study was designed to rigorously test the notion of action prediction-based sensory attenuation. Participants performed one of four voluntary actions on each trial, with each button associated with either predictable or unpredictable action effects. In addition, actions with each hand could result in action effects that were either congruent or incongruent with hand-specific prediction. We observed no significant differences in N1 amplitude between predictable and unpredictable tones. When contrasting action effects that were congruent or incongruent with hand-specific prediction, we observed significant attenuation for prediction-congruent compared to prediction-incongruent action-effects. These novel findings suggest that accurate action-effect prediction drives sensory attenuation of auditory stimuli. These findings have important implications for understanding the mechanisms of action-effect prediction and sensory attenuation, and may have clinical implications for studies investigating action awareness and agency in schizophrenia.