Do F-wave measurements detect changes in motor neuron excitability?
Do F-wave measurements detect changes in motor neuron excitability?
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DOI：
10.1002/mus.20110
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发表时间：
2004-09-01
期刊：
影响因子：
3.4
通讯作者：
Floeter, MK
中科院分区：
文献类型：
--
作者：
Lin, JZ;Floeter, MK
在实验范式中使用 F 波评估运动神经元兴奋性从未得到验证。我们的目标是确定 F 波面积、振幅和持久性测量值是否会因已知会改变运动神经元兴奋性的操作而发生变化。在 12 名健康志愿者中评估了肌肉振动、远端肌肉收缩和同侧、对侧手指高强度刺激的影响。 F 波面积、振幅和持续时间均随同侧皮肤刺激而下降。其他操作有助于部分（但不是全部）F 波测量。 F波面积和振幅的变化是相关的，但与持续性的变化都不相关。需要 50-75 F 波的样本大小来近似 100 F 波的振幅和面积结果，精度为 +/-25%。我们得出的结论是，F 波的变化更能检测运动神经元的抑制作用，而不是促进作用。 F 波以一般方式反映运动神经元的兴奋性，但无法准确测量兴奋性的短期变化。
The use of F waves to assess motor neuron excitability in experimental paradigms has never been validated. Our objective was to determine whether F-wave area, amplitude, and persistence measurements change in response to manipulations known to alter the excitability of motor neurons. The effects of muscle vibration, contraction of a remote muscle, and high-intensity stimulation of ipsilateral o, contralateral fingers were assessed in 12 healthy volunteers. F-wave area, amplitude, and persistence all declined with ipsilateral cutaneous stimulation. The other maneuvers facilitated some, but not all, of the F-wave measurements. Changes in F-wave area and amplitude were correlated, but neither correlated with changes in persistence. A sample size of 50-75 F waves was needed to approximate amplitude and area results from 100 F waves with an accuracy of +/-25%. We conclude that changes in F waves are better at detecting inhibition than facilitation of motor neurons. F waves reflect motor neuron excitability in a general way but do not allow for accurate measures of short-term changes in excitability.