Minimal Awareness and Stalled Uptake of Pre-Exposure Prophylaxis (PrEP) Among at Risk, HIV-Negative, Black Men Who Have Sex with Men
Minimal Awareness and Stalled Uptake of Pre-Exposure Prophylaxis (PrEP) Among at Risk, HIV-Negative, Black Men Who Have Sex with Men
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DOI：
10.1089/apc.2014.0303
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发表时间：
2015-08-01
影响因子：
4.9
通讯作者：
Conway-Washington, Christopher
中科院分区：
文献类型：
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作者：
Eaton, Lisa A.;Driffin, Daniel D.;Conway-Washington, Christopher
在美国，艾滋病毒感染率在与男性发生性关系的黑人男性（BMSM）中最高。暴露前预防（PrEP）是一种非常有效的艾滋病毒预防形式，但自2012年FDA批准以来，这一策略的采用一直很缓慢，目前还不清楚有关PrEP的信息是否到达BMSM。从2012年1月（PrEP批准前6个月）到2014年3月（批准后20个月），对佐治亚州亚特兰大的436名BMSM进行了调查。分析显示，调查评估日期与对PrEP的了解之间没有关联（20.5%在批准前了解PrEP，23.4%在批准后了解; OR=0.99 [0.98-1.02]，p=0.952）。在一个多变量模型中，不知道PrEP的BMSM报告了较低的HIV检测知识率，较少的HIV检测经验，我们的研究结果表明，人们对PrEP的理解有限，为了获得PrEP的全部益处，需要进行大量的基础工作。目前的研究结果呼吁人们注意这两方面的必要性。优先考虑并更好地了解如何加强医学进步和社区吸收之间的桥梁。
In the United States, rates of HIV infection are highest among black men who have sex with men (BMSM). Pre-exposure prophylaxis (PrEP) is a highly effective form of HIV prevention, but the uptake of this strategy has been slow since FDA approval in 2012, and it is unknown whether information about PrEP is reaching BMSM. Four hundred and thirty-six BMSM in Atlanta, GA were surveyed from January 2012 (6 months prior to PrEP approval) to March 2014 (20 months after approval). Analyses revealed no association between date of survey assessment and awareness of PrEP (20.5% were aware of PrEP before approval and 23.4% were aware after approval; OR=0.99 [0.98-1.02], p=0.952). In a multivariate model, BMSM unaware of PrEP reported lower rates of HIV testing knowledge, fewer experiences with HIV testing, and higher rates of transactional sex than BMSM who were aware of PrEP. Our findings suggest that there is limited understanding of PrEP and that there is considerable groundwork that needs to be achieved in order to reap the full benefits of PrEP. The current findings call attention to the need to both prioritize and better understand how to strengthen the bridge between medical advances and community uptake.