Music Reduces Pain Unpleasantness: Evidence from an EEG Study
Music Reduces Pain Unpleasantness: Evidence from an EEG Study
复制标题
音乐减少疼痛不适：来自脑电图研究的证据
DOI：
10.2147/jpr.s212080
复制
发表时间：
2019-01-01
影响因子：
2.7
通讯作者：
Hu, Li
中科院分区：
文献类型：
--
作者：
Lu, Xuejing;Thompson, William Forde;Hu, Li
背景：音乐有时被用作疼痛管理的辅助手段。然而，音乐通过什么方式调节疼痛感知以及大脑如何在听音乐时对伤害性输入做出反应的理解有限，因为临床实践通常涉及多种治疗干预的共存。为了应对这一挑战，实验室研究与实验和控制conditions.Methods：在目前的调查中，我们提供伤害性激光刺激30名参与者在三种条件下-参与者坐在沉默，听他们喜欢的音乐，或听白色噪音。条件之间的差异进行了量化的自我报告的疼痛强度和不愉快，大脑活动采样脑电图（EEG）。结果：与噪音和沉默的条件相比，在音乐条件下的参与者报告较低的评级疼痛不愉快，反映了减少脑振荡之前立即伤害性激光刺激在EEG中的频率为4-15 Hz。此外，参与者在听音乐或白色噪音时的激光诱发电位（LEPs）中显示出较小的P2振幅，而不是安静地坐着。这些研究结果表明，一般的声音对疼痛的调制效果，与特定的减少疼痛不愉快引起的积极的情绪impacts.Conclusion：音乐可以作为一个实时调节疼痛不愉快。结果进行了讨论，鉴于目前的理解音乐诱导镇痛。
Background: Music is sometimes used as an adjunct to pain management. However, there is limited understanding of by what means music modulates pain perception and how the brain responds to nociceptive inputs while listening to music, because clinical practice typically involves the coexistence of multiple therapeutic interventions. To address this challenge, laboratory studies with experimental and control conditions are needed.Methods: In the present investigation, we delivered nociceptive laser stimuli on 30 participants under three conditions - participants were sitting in silence, listening to their preferred music, or listening to white noise. Differences among conditions were quantified by self-reports of pain intensity and unpleasantness, and brain activity sampled by electro-encephalography (EEG).Results: Compared with the noise and silence conditions, participants in the music condition reported lower ratings on pain unpleasantness, as reflected by reduced brain oscillations immediately prior to the nociceptive laser stimulus at frequencies of 4-15 Hz in EEG. In addition, participants showed smaller P2 amplitudes in laser-evoked potentials (LEPs) when they were listening to music or white noise in comparison to sitting in silence. These findings suggest that a general modulation effect of sounds on pain, with a specific reduction of pain unpleasantness induced by the positive emotional impact.Conclusion: Music may serve as a real-time regulator to modulate pain unpleasantness. Results are discussed in view of current understandings of music-induced analgesia.