Physical Strain: A New Perspective on Walking in Cerebral Palsy

Physical Strain: A New Perspective on Walking in Cerebral Palsy
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DOI:
10.1016/j.apmr.2017.05.004
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发表时间:
2017-12-01
影响因子:
4.3
通讯作者:
Dallmeijer, Annet J.
Dallmeijer, Annet J.
中科院分区:
医学1区
文献类型:
--
作者:
Balemans, Astrid C.;Bolster, Eline A.;Dallmeijer, Annet J.

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目的:描述(1)步行的体力紧张,(2)步行超过无氧阈值的参与者的比例,(3)基于有氧能力和步行能量消耗(EC)的偏差,描述4种步行体力紧张的表型。设计:队列研究。地点:学术医学中心。参与者:样本(N=57)参与者(n=37;平均年龄13.5+/-4.0岁,粗大运动功能分级系统I级[13]、II级[17]和BI级[7])和典型发展中(TD)参与者(n=20;平均年龄11.8+/-3.5岁)。干预:不适用。主要观察指标:以舒适的速度步行时测定氧耗(Vo(2)步行)、速度和EC。在最大负荷自行车运动试验中测量最大耗氧量(Vo(2)峰值)和无氧阈值。低于10百分位数则有氧能力下降,高于3SD则EC增加。躯体应激定义如下:(Vo(2)Walk/DVO(2)峰值)x100。结果:慢性阻塞性肺病患者的躯体应激(GMFCS I级,55%+/-12%GMFCS II级,62%+/-17%;GMFCS III级,78%+/-14%)明显高于TD组(40%+/-11%)(P
Objectives: To describe (1) physical strain of walking, (2) the proportion of participants walking above the anaerobic threshold, and (3) 4 phenotypes of physical strain of walking on the basis of deviations in aerobic capacity and walking energy cost (EC) in children and adolescents with cerebral palsy (CP).Design: Cohort study.Setting: Academic medical center.Participants: A sample (N=57) of participants (n=37; mean age, 13.5 +/- 4.0y) with CP (Gross Motor Function Classification System [GMFCS] levels I [n=13], II [n=17], and BI [n=7]) and typically developing (TD) participants (n=20; mean age, 11.8 +/- 3.5y).Interventions: Not applicable.Main Outcome Measures: Oxygen consumption (Vo(2)walk), speed, and EC were determined during walking at a comfortable speed. Peak oxygen consumption (Vo(2)peak) and anaerobic threshold were measured during a maximal cycling exercise test. Aerobic capacity was reduced if lower than the 10th percentile, and EC was increased if higher than 3SD. Physical strain was defined as follows: (Vo(2)walk/dVo(2)peak)x100.Results: Participants with CP had a higher physical strain (GMFCS level I, 55%+/- 12% GMFCS level II, 62%+/- 17%; GMFCS level III, 78%+/- 14%) than did TD participants (40%+/- 11%) (P