Instrumental learning and relearning in individuals with psychopathy and in patients with lesions involving the amygdala or orbitofrontal cortex.
Instrumental learning and relearning in individuals with psychopathy and in patients with lesions involving the amygdala or orbitofrontal cortex.
复制标题
精神病患者和杏仁核或眶额皮质病变患者的工具学习和再学习。
DOI：
10.1037/0894-4105.20.3.280
复制
发表时间：
2006
期刊：
影响因子：
2.4
通讯作者：
Blair,RJR
中科院分区：
文献类型：
--
作者：
Mitchell,DGV;Fine,C;Richell,RA;Newman,C;Lumsden,J;Blair,KS;Blair,RJR
先前的研究表明，精神病患者在某些形式的联想学习上受损，特别是刺激强化学习（Blair et al., 2004; Newman & Kosson, 1986）。动物实验表明，获得刺激-强化关联需要杏仁核（Baxter & Murray, 2002）。精神病患者也表现出较差的逆向学习（Mitchell, Colledge, Leonard, & Blair, 2002）。反转学习是由腹外侧和眶额皮质支持的（Rolls, 2004）。在这篇论文中，我们提出了实验研究刺激-强化学习和再学习在眼窝前额皮质或杏仁核损伤患者和没有已知创伤的发展性精神病患者中的作用。研究结果与当前刺激强化学习、再学习和发展性精神病的神经认知模型有关。（PsycINFO数据库记录(c) 2019 APA，版权所有）
Previous work has shown that individuals with psychopathy are impaired on some forms of associative learning, particularly stimulus-reinforcement learning (Blair et al., 2004; Newman & Kosson, 1986). Animal work suggests that the acquisition of stimulus-reinforcement associations requires the amygdala (Baxter & Murray, 2002). Individuals with psychopathy also show impoverished reversal learning (Mitchell, Colledge, Leonard, & Blair, 2002). Reversal learning is supported by the ventrolateral and orbitofrontal cortex (Rolls, 2004). In this paper we present experiments investigating stimulus-reinforcement learning and relearning in patients with lesions of the orbitofrontal cortex or amygdala, and individuals with developmental psychopathy without known trauma. The results are interpreted with reference to current neurocognitive models of stimulus-reinforcement learning, relearning, and developmental psychopathy.(PsycINFO Database Record (c) 2019 APA, all rights reserved)