Stereochemical preference for heterochiral coupling controls selectivity in competitive peptide synthesis

Stereochemical preference for heterochiral coupling controls selectivity in competitive peptide synthesis
复制标题

异手性偶联的立体化学偏好控制竞争性肽合成的选择性

DOI:
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发表时间:
1999
期刊:
影响因子:
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通讯作者:
Graham E. Jeffs
Graham E. Jeffs
中科院分区:
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文献类型:
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作者:
D. Birch;M. North;R. Hill;Graham E. Jeffs

文献摘要

被引文献

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Competitive activated couplings of N-phthaloyl amino acids with amino acid dimethylamides show little selectivity among substrates in respect of their sidechains, but a consistent and significant preference for heterochiral outcomes.