Axial area and anteroposterior diameter as estimates of left atrial size using computed tomography of the chest: comparison with 3-dimensional volume.

Axial area and anteroposterior diameter as estimates of left atrial size using computed tomography of the chest: comparison with 3-dimensional volume.
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DOI:
10.1016/j.jcct.2009.10.013
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发表时间:
2010-01
影响因子:
5.4
通讯作者:
Hoffmann, Udo
Hoffmann, Udo
中科院分区:
医学3区
文献类型:
--
作者:
Mahabadi, Amir A.;Truong, Quynh A.;Schlett, Christopher L.;Samy, Bharat;O'Donnell, Christopher J.;Fox, Caroline S.;Bamberg, Fabian;Hoffmann, Udo

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左心房(LA)大小在危险分层中具有递增价值。我们的目的是通过胸部CT(轴向LA面积和LA前后[AP]直径)使用对比增强和CT扫描评估两种快速测量LA大小的可行性和可重复性。我们在100个对比增强的64层MDCT扫描(从ROMICAT集合中随机选择)中通过1)左心室流出道和二尖瓣瓣叶水平的轴向LA面积,2)三腔视图中的AP直径和3)Simpson方法的三维(3D)LA体积测量LA尺寸。我们评估了观察者间和观察者内的组内相关系数(ICC),包括轴向LA面积和AP直径以及它们与3D LA体积的相关性。对于轴向区域,还在100个非造影剂MDCT扫描中确定了可行性和再现性,这些扫描是从Fractionary Heart Offspring集体中随机选择的。在增强CT中,左心房轴向面积和AP直径具有良好的再现性(观察者间:轴向面积:ICC 0.96,平均相对差2.4± 7.4%,AP直径:ICC 0.91,3.6±7.2%;观察者内:轴向面积:ICC 0.99,0.4± 5.2%,AP直径:ICC 0.94,1.7±5.5%)。与3D体积的相关性轴向面积(r=0.88)比AP直径(r=0.67)更好。在非造影图像中,轴向面积的评估具有良好的重现性(观察者间:ICC 0.96,0.5±8.3%;观察者内:ICC 0.99,0.01±4.4%)。AP直径和轴向LA面积允许在对比增强和非对比ECG门控胸部CT中快速和可重复地估计LA体积。然而,LA面积应优于AP直径,因为其与3D LA体积的一致性更好。
Left atrial (LA) size has incremental value in risk stratification. We aim to assess feasibility and reproducibility of two quick measures of LA size by chest CT (axial LA area and LA anterior-posterior [AP] diameter) using contrast-enhanced and CT scans. We measured LA size in 100 contrast-enhanced 64-slice MDCT scans (randomly selected from the ROMICAT collective) by 1) axial LA area at the level of the left ventricular outflow tract and the mitral valve leaflets, 2) AP-diameter in 3-chamber view, and 3) three-dimensional (3D) LA volume by Simpson's methods. We assessed inter- and intraobserver intraclass correlation coefficient (ICC) for axial LA area and AP-diameter as well as their correlation to 3D LA volume. For axial area, feasibility and reproducibility were also determined in 100 non-contrast MDCT scans, randomly selected from the Framingham Heart Offspring collective. In contrast-enhanced CT, both LA axial area and AP-diameter had excellent reproducibility (Interobserver: Axial area: ICC 0.96, mean relative difference 2.4±7.4%, AP-diameter: ICC 0.91, 3.6±7.2%; Intraobserver: Axial area: ICC 0.99, 0.4±5.2%, AP-diameter: ICC 0.94, 1.7±5.5%). Correlations with 3D volume were better for axial area (r=0.88) than for AP-diameter (r=0.67). In non-contrast images, axial area could be assessed with excellent reproducibility (Interobserver: ICC 0.96, 0.5±8.3%; Intraobserver: ICC 0.99, 0.01±4.4%). Both AP-diameter and axial LA area permit quick and reproducible estimates of LA volume in contrast-enhanced and non-contrast ECG-gated chest CT. However, LA area should be used preferably over AP-diameter because of its better agreement to 3D LA volume.
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